University Of Birmingham

This study is for children with hepatoblastoma or hepatocellular carcinoma, two types of liver cancer. It uses a risk-adapted approach, meaning treatment is tailored to each child's specific situation. The main goal is to see how long children can live without the cancer coming b…

This study looks at ways to improve stem cell transplants for older adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It compares different pre-transplant and conditioning therapies to reduce relapse and improve survival. About 333 participants…

This phase 3 trial compares different treatment combinations for people with intermediate or high-risk oropharyngeal cancer (a type of throat cancer). The goal is to find which approach works best to improve survival and reduce severe side effects. About 785 participants are bein…

This study compares two different chemotherapy and radiation regimens given before a stem cell transplant for adults with acute lymphoblastic leukemia (ALL) in remission. The goal is to see if a stronger regimen can reduce the chance of the cancer returning without increasing the…