University Of Birmingham

This study tested whether adding the drug bevacizumab (which blocks blood vessel growth to tumors) to standard chemotherapy helps children with neuroblastoma that has come back or not responded to treatment. It also looked at adding other chemotherapy drugs like irinotecan or top…

This study tested whether sodium valproate, a drug already used for other conditions, can help people with Wolfram syndrome—a rare genetic disorder that causes diabetes, vision loss, and other problems. The trial included 63 children and adults who were randomly assigned to recei…

This trial tested several targeted drugs in people with non-small cell lung cancer whose tumors had specific genetic markers. The goal was to see if these drugs could shrink tumors or delay cancer growth. Over 400 participants received treatment tailored to their cancer's genetic…

This study tested the drug nivolumab in 35 people with a certain kind of advanced colorectal cancer that has not responded to standard treatments. The goal was to see if the drug could stop the cancer from growing for at least 27 weeks. The trial is complete, and results help und…

This study looked at whether a cocoa drink rich in flavanols could protect blood vessel function and blood pressure in healthy older adults (65+) during 2 hours of sitting. Twenty participants drank either a high-flavanol or low-flavanol cocoa before sitting, and their artery hea…