Hope for kids with tough cancer: new drug combo shows promise
NCT ID NCT02308527
First seen May 12, 2026 · Last updated May 23, 2026 · Updated 2 times
Summary
This study tested whether adding the drug bevacizumab (which blocks blood vessel growth to tumors) to standard chemotherapy helps children with neuroblastoma that has come back or not responded to treatment. It also looked at adding other chemotherapy drugs like irinotecan or topotecan, and the immunotherapy dinutuximab beta. The trial included 225 children aged 1 to 21 and measured tumor shrinkage and side effects. The goal was to find better treatment options for this hard-to-treat cancer.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hopital des Enfants
Toulouse, 31059, France
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Instituto de Investigacion Sanitaria
Valencia, 46026, Spain
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Natasha van Eijkelenburg
Utrecht, Netherlands
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Ospedale Pediatrico Bambino Gseu
Rome, 00165, Italy
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Our Ladys Children's Hospital Dublin
Dublin, Dublin 12, Ireland
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St Anna Children's Hospital and CCRI/Studies and Statistics
Vienna, A-1090, Austria
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Swiss Paediatric Oncology Group
Bern, 3008, Switzerland
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The Royal Marsden NHS Foundation Trust and Institute of Cancer Research
Sutton, Surrey, SM2 5PT, United Kingdom
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University Hospital
Ghent, Belgium
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University Hospital Rigshospitalet
Copenhagen, DK-2100, Denmark
Conditions
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