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Massive UK study tracks cancer after organ transplants

NCT ID NCT02991105

Knowledge-focused Sponsor: University of Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why people who have had an organ transplant are more likely to get cancer. Researchers will combine existing health records from over 85,000 transplant patients in England to track cancer cases and deaths. The goal is to better understand risks and improve care for transplant recipients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 85,410 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 1985

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

85,410 solid organ transplant have been performed in England between 01/01/1985 and 31/12/2015.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Solid organ transplant recipient, transplant performed in England Exclusion Criteria: * Transplant performed in Scotland, Wales or Northern Ireland * Any living transplant recipient who wishes to opt-out of the anonymised record linkage (contact study lead: central contact person)

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Conditions

The condition(s) this trial relates to.

cancer disease related to solid organ transplantation disease related to transplantation heart failure kidney failure liver failure neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Heart failure Kidney failure Liver failure Malignancy Transplant complication

Contacts and locations

Locations

  • University of Birmingham

    Birmingham, B15 2TT, United Kingdom

  • University of Birmingham, Edgbaston

    Birmingham, West Midlands, B15 2TT, United Kingdom

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