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New hope for throat cancer patients: landmark trial tests smarter treatments

NCT ID NCT04116047

First seen May 17, 2026 · Last updated May 20, 2026 · Updated 1 time

Summary

This phase 3 trial compares different treatment combinations for people with intermediate or high-risk oropharyngeal cancer (a type of throat cancer). The goal is to find which approach works best to improve survival and reduce severe side effects. About 785 participants are being studied across multiple hospitals.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aberdeen Royal Infirmary

    Aberdeen, Aberdeen, AB25 2ZN, United Kingdom

  • Addenbrooke's Hospital

    Cambridge, CB2 0QQ, United Kingdom

  • Aintree University Hospital

    Liverpool, L9 7AL, United Kingdom

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Belfast City Hospital

    Belfast, BT9 7AB, United Kingdom

  • Bradford Royal Infirmary

    Bradford, West Yorkshire, BD9 6RJ, United Kingdom

  • Bristol Haematology and Oncology Centre

    Bristol, Bristol, BS2 8ED, United Kingdom

  • Castle Hill Hospital

    Cottingham, East Yorkshire, HU16 5JQ, United Kingdom

  • Cheltenham General Hospital

    Cheltenham, GL53 7AN, United Kingdom

  • Christie Hospital

    Manchester, M20 4BX, United Kingdom

  • Churchill Hospital

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • Clatterbridge Cancer Centre

    Metropolitan Borough of Wirral, CH63 4JY, United Kingdom

  • Colchester General Hospital

    Colchester, Essex, CO4 5JL, United Kingdom

  • Derriford Hospital

    Plymouth, United Kingdom

  • Freeman Hospital

    Newcastle upon Tyne, Tyne and Wear, NE7 7DN, United Kingdom

  • James Cook University Hospital

    Middlesbrough, North Yorkshire, TS4 3BW, United Kingdom

  • Leicester Royal Infirmary

    Leicester, East Midlands, LE1 5WW, United Kingdom

  • Musgrove Park Hospital

    Taunton, TA1 5DA, United Kingdom

  • Newcross Hospital

    Wolverhampton, West Midlands, WV10 OQP, United Kingdom

  • Norfolk and Norwich University Hospital

    Norwich, NR4 7UY, United Kingdom

  • North Middlesex Hospital

    London, London, N18 1QX, United Kingdom

  • Nottingham City Hospital

    Nottingham, Nottingham, NG5 1PB, United Kingdom

  • Queen Elizabeth Hospital

    Birmingham, West Midlands, B15 2TH, United Kingdom

  • Queen's Hospital

    Romford, Essex, RM7 0AG, United Kingdom

  • Royal Devon and Exeter Hospital

    Exeter, Devon, EX2 5DW, United Kingdom

  • Royal Preston Hospital

    Preston, Lancashire, PR2 9HT, United Kingdom

  • Royal Shrewsbury Hospital

    Shrewsbury, SY3 8XQ, United Kingdom

  • Royal United Hospital

    Bath, BA1 3NG, United Kingdom

  • Singleton Hospital

    Swansea, Swansea, SA2 8QA, United Kingdom

  • St James's Hospital

    Dublin, Dublin 8, Ireland

  • St James's University Hospital

    Leeds, West Yorkshire, LS9 7TF, United Kingdom

  • St Luke's Hospital

    Dublin, Dublin 6, Ireland

  • Torbay Hospital

    Torquay, TQ2 7AA, United Kingdom

  • University Hospital Coventry

    Coventry, West Midlands, CV2 2DX, United Kingdom

  • Velindre Cancer Centre

    Cardiff, Cardiff, CF14 2TL, United Kingdom

  • Western General Hospital

    Edinburgh, Edinburgh, EH4 2XU, United Kingdom

  • Weston Park Hospital

    Sheffield, South Yorkshire, S10 2SJ, United Kingdom

  • York Hospital

    York, North Yorkshire, YO31 8HE, United Kingdom

Conditions

Explore the condition pages connected to this study.