University Of Alabama At Birmingham

This early-phase trial tested the safety of giving a second dose of an experimental virus (C134) directly into the brain tumor of people with recurrent malignant glioma, a fast-growing brain cancer. Only one person enrolled before the study was stopped. The goal was to see if rep…

This early-stage study tested the safety of the drug tazemetostat in people with a rare type of blood cancer called peripheral T-cell lymphoma that had come back or not responded to treatment. Only 6 people took part before the study was stopped. The goal was to find a safe dose …

This study tested whether giving the HPV vaccine to adults aged 18-45 in the emergency department could increase vaccination rates. Researchers planned to enroll 34 people who had not completed the vaccine series. The study was terminated early, so results are limited.

This study aimed to see if acceptance and commitment therapy (ACT), a type of talk therapy, could help HIV-positive men deal with general mental health issues like stress, anxiety, and depression. Only one person enrolled before the study was stopped early. The therapy focused on…

This study tested a program to improve quality of life for young African American women who finished treatment for early or late-stage breast cancer. About 27 women took part in either the program or a comparison group. The goal was to see if the program helped with physical, emo…

This study tested a program called Y-AMBIENT, designed to improve quality of life for young African American women (ages 18-44) with stage I-III breast cancer who were undergoing chemotherapy or radiation. The program involved phone sessions, videos, and written materials over fo…

This study looked at whether a vaginal estrogen cream could help women recover from serious tears during childbirth (called obstetric anal sphincter injuries). The cream was started two weeks after giving birth and compared to a placebo. The goal was to see if it improved sexual …

This study looked at two ways to immobilize a child's broken forearm: a cast that keeps the elbow bent versus one that keeps it straight. The goal was to see which method keeps the bones aligned and causes fewer problems like slipping or burns. Only 3 children took part before th…

This study looked at whether adding baclofen (a muscle relaxant) to buprenorphine (a painkiller) could improve pain relief in healthy adults. Researchers measured how participants reacted to heat pain after taking the drugs. The study was stopped early and involved 19 people.

This study tested whether a dye called indocyanine green, which glows under special cameras, helps surgeons find and protect parathyroid glands during thyroid or parathyroid surgery. Over 400 adults were enrolled, but the study was stopped early. The goal was to see if the dye ma…