The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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Could stem cells restore sexual function after prostate surgery?
Disease control Not yet recruitingThis study tests whether injecting stem cells from donated fat tissue can help men recover the ability to have erections after prostate cancer surgery. Forty men aged 40 to 70 with early-stage prostate cancer will receive either stem cells or a placebo. The goal is to see if the …
Phase: PHASE1, PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 26, 2026 05:16 UTC
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Spine surgery antibiotic showdown: bone injection vs. IV
Disease control Not yet recruitingThis study tests if giving the antibiotic vancomycin directly into the bone during lumbar fusion surgery works as well as or better than the usual method through a vein. Thirty adults having spine surgery will be randomly assigned to one of the two methods. Researchers will measu…
Phase: PHASE2, PHASE3 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New blood test may personalize leukemia treatment, avoiding harsh chemo
Disease control Not yet recruitingThis study tests a new blood test (5hmC) to see how well acute myeloid leukemia (AML) is responding to treatment. About 112 adults with newly diagnosed AML will get either a milder drug (hypomethylating agent) or standard strong chemo. The test helps doctors decide if more treatm…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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High-Dose steroid may ease stent pain after kidney stone surgery
Symptom relief Not yet recruitingThis study tests whether a high dose (20 mg) of the steroid dexamethasone works better than a standard dose (4 mg) at reducing urinary symptoms and pain after kidney stone surgery that requires a temporary ureteral stent. About 70 adults will receive one dose during surgery and r…
Phase: PHASE1, PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated May 18, 2026 12:13 UTC
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New study tests antibiotic injection into bone for knee surgery
Knowledge-focused Not yet recruitingThis study compares giving the antibiotic vancomycin directly into the ankle bone versus through a vein during revision knee replacement surgery. Researchers want to see which method delivers higher antibiotic levels to the knee area. The study involves 40 adults undergoing revis…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC