The Methodist Hospital Research Institute

This study is testing whether adding a drug called belumosudil to standard anti-rejection medications can prevent scarring in newly transplanted kidneys. Researchers want to see if blocking a specific biological pathway can reduce structural damage that often leads to transplant …

This early-stage trial is testing whether two existing drugs, olaparib and vorinostat, can be safely used together to treat advanced breast cancer that has returned or spread. The study aims to find the safest dose and see if blocking two of the cancer's repair mechanisms helps c…

This study is testing if giving an immunotherapy drug called atezolizumab before surgery is safe for people with high-risk skin melanoma that hasn't spread. The drug aims to help the patient's own immune system fight the cancer, potentially lowering the chance of it coming back a…

This study is testing a new two-part treatment for muscle-invasive bladder cancer in patients who cannot receive standard chemotherapy. Before having their bladder surgically removed, participants receive a drug called sasanlimab (an immunotherapy) and a short, precise course of …

This study is testing if injecting an antibiotic directly into the shoulder bone during replacement surgery is as effective as the standard method of giving it through an IV. Researchers are comparing the two methods in 33 patients to see if both deliver similar antibiotic levels…