The Methodist Hospital Research Institute

This early-phase study tested whether adding L-NMMA to the immunotherapy drug pembrolizumab is safe for people with several advanced cancers, including melanoma, lung cancer, and others. The goal was to see if blocking a signal that protects cancer cells could help the immune sys…

This early-phase study tested whether a combination of two drugs, abatacept and interleukin-2, is safe for people with ALS. The goal was to increase the number and activity of regulatory T cells, which may help slow the disease. Five participants were enrolled, and the main focus…

This study tested whether giving plasma from people who recovered from COVID-19 to those with severe COVID-19 is safe and helpful. 350 adults received the plasma treatment. The main goals were to check for serious side effects and see if it lowered the chance of death within 28 d…

This study tested two different contrast agents (Dotarem and Gadovist) used during heart MRI scans to see if they produce equally clear images. 120 adults with coronary artery disease or cardiomyopathy were randomly assigned to receive one of the two agents. The goal was to compa…

This small study looked at whether 10 sessions of electro-acupuncture (acupuncture with mild electric pulses) could help people with nerve pain or numbness from chemotherapy. Twenty adults who had finished certain chemo drugs at least 3 months earlier took part. The main goal was…

This study tested a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) for adults with overactive bladder (OAB). 14 participants received brain stimulation to see if it could improve bladder control and reduce urgency. The goal was to understand how…

This study tested whether using a virtual reality (VR) program called ReCognitionVR is practical and safe for older adults recovering from abdominal surgery. Thirty patients aged 60 and older used the VR software or standard orientation methods. The goal was to see if VR could he…