The Methodist Hospital Research Institute

This early-stage study tested a combination of an immunotherapy drug (atezolizumab) and a gene therapy (ADV/IL-12) in 13 people with advanced non-small cell lung cancer that had worsened after initial immunotherapy. The main goal was to check safety and see if the combination cou…

This study tested a combination of chemotherapy, an immunotherapy drug (pembrolizumab), and gene therapy (IL-12) in 8 women with a tough-to-treat type of breast cancer (triple negative) that had stopped responding to standard treatment. The goal was to see if the combination coul…

This study aimed to see if a knee isometric exercise program could reduce anterior knee pain and improve function better than standard physical therapy. It planned to enroll adults aged 18-65 with knee pain lasting 4 weeks to 12 months. However, the study was terminated early aft…

This study aimed to check the safety of a rabies immune globulin product (HyperRAB) in children up to 17 years old who received it after an animal bite. Researchers tracked side effects for up to 30 days. The study was stopped early, but the information gathered helps doctors und…