The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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Gene therapy joins fight against tough breast cancer
Disease control TerminatedThis study tested a combination of three treatments for an aggressive type of breast cancer that had stopped responding to standard chemotherapy. It combined chemotherapy (docetaxel), an immunotherapy drug (pembrolizumab), and a gene therapy designed to boost the immune system. T…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New gene therapy tested for Tough-to-Treat lung cancer
Disease control TerminatedThis early-stage study tested the safety of combining an existing immunotherapy drug (atezolizumab) with a new gene therapy (ADV/IL-12) for patients with advanced non-small cell lung cancer. The trial was for people whose cancer had continued to grow despite receiving standard fi…
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Can simple exercises beat standard knee pain treatment?
Symptom relief TerminatedThis study tested if a specific set of knee-strengthening exercises (called a knee isometric program) worked better than the usual physical therapy for reducing pain in the front of the knee. A small group of adults with knee pain were randomly assigned to try one of the two exer…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Mar 24, 2026 12:01 UTC
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Doctors track Kids' reactions to Life-Saving rabies shot
Knowledge-focused TerminatedThis study observed children (age 17 and under) who received a standard rabies prevention shot after an animal bite or scratch. Researchers tracked any side effects for 30 days to confirm the shot's safety in kids. The study did not test a new treatment but monitored the safety o…
Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC