The Children's Hospital Of Zhejiang University School Of Medicine

This study tests a new surgical technique (urethral plate flap) against the standard method (tunica vaginalis flap) for fixing severe penile curvature in children with hypospadias. About 90 children aged 6 months to 14 years will take part. The goal is to see if the new method wo…

This study tests a new home-based lung exercise program for children aged 6 to 12 with asthma. The program is designed to be led by families and aims to improve asthma control. Researchers will compare this program to standard care in 92 children over 12 weeks, with follow-up for…

This study tests a cream called ruxolitinib phosphate in children aged 2 to 11 with non-segmental vitiligo, a condition that causes white patches on the skin. The goal is to see if the cream can safely bring back skin color over 24 weeks. About 20 children will apply the cream da…

This study looks at whether a drug called telitacicept can help children aged 3-17 with IgA vasculitis nephritis, a condition that causes kidney inflammation. Researchers will compare telitacicept to standard steroid treatment to see which better reduces protein in the urine and …

This study looks at whether giving children with Crohn's disease a combination of two drugs (infliximab and azathioprine) works better than just one drug (infliximab) to control the disease. About 154 children will take either the combo or the single drug for over a year. The goa…

This study tests a new drug called Telitacicept in 30 children with ocular myasthenia gravis, a condition that causes eye muscle weakness. The goal is to see if the drug can better control symptoms and reduce the need for steroids, which have side effects. Participants will recei…

This study tests whether giving the drug lidocaine during heart surgery can reduce lung damage in infants. About 320 babies under 1 year old with congenital heart disease will receive either lidocaine or a placebo. The goal is to see if lidocaine helps them breathe better and rec…

This study aims to see if using a child's genetic information to adjust the dose of a chemotherapy drug (6-MP) can reduce dangerous side effects like low white blood cell counts and infections. About 110 children with acute lymphoblastic leukemia will receive personalized dosing …

This study looks at the best way to feed very premature babies (born before 29 weeks) when their mother's milk isn't enough. It compares donor human milk versus special formula, and also tests whether adding extra nutrients to milk should be routine or only when growth is slow. T…

This study will test whether an artificial intelligence (AI) system can accurately diagnose inherited metabolic disorders in newborns during routine screening. Researchers will compare the AI's results to standard manual interpretation by trained staff. The goal is to see if the …

This study looks at whether a blood test for a substance called copeptin can help doctors diagnose and classify bedwetting in children aged 5 to 18. Currently, diagnosis relies on a detailed urine diary, which is often inaccurate and inconvenient. The goal is to find a simpler, m…

This study tests two different ways of giving the steroid dexamethasone to very premature babies (born at 24-29 weeks) who need a breathing machine. The goal is to see which method better prevents bronchopulmonary dysplasia (BPD), a serious chronic lung disease, or death. About 9…

This study tests a new system that uses optical motion capture to help doctors locate kidney stones more quickly during ultrasound-guided shock wave treatment. About 80 children with upper urinary tract stones will be randomly assigned to either the new motion-capture method or t…

This study tests whether playing active video games (exergames) on a Nintendo Switch can help children and teenagers with congenital heart disease become more physically active. The study will include 13 participants aged 8-18 who are stable after heart surgery. They will wear ac…

This study looks at when to perform a bronchoscopic lung washout in children with severe pneumonia to help them recover faster. About 3,168 children will be enrolled to see if earlier or later treatment improves breathing, reduces hospital stay, and lowers costs. The goal is to c…

This study is testing whether breathing in a gas called xenon for 10 minutes each day can help children with autism spectrum disorder (ASD) improve their social skills. The trial will involve 72 children aged 4 to 18 who will receive either xenon or a placebo gas for 10 days. Res…

This study tests a digital exercise program that adjusts in real time to help children aged 6-12 recover after congenital heart disease surgery. Kids wear non-invasive monitors and follow daily exercises guided by a smartphone system. Researchers will compare their recovery with …

This study will follow 330 infants diagnosed with congenital hydronephrosis (a common kidney condition) before 6 months of age. Over 3 years, researchers will track whether the condition improves, worsens, or stays the same using ultrasound scans. The goal is to learn the natural…

This study will create a structured follow-up program for 400 children and young adults who have survived blood cancers like leukemia and lymphoma. The goal is to better track and manage long-term health problems that can appear years after treatment. Researchers will use an elec…

This study looks at why some teen girls (ages 9-17) and their parents are hesitant about the HPV vaccine, which prevents certain cancers. It will test a program that provides easy-to-understand materials, support during doctor visits, and reminders to help families make informed …

This study looks at why some young children get severe tooth decay that keeps coming back. Instead of only looking at teeth, researchers will also study family stress, children's behavior, and sleep patterns. They plan to collect data from 1,200 preschool children and their paren…