Sunnybrook Health Sciences Centre
Clinical trials sponsored by Sunnybrook Health Sciences Centre, explained in plain language.
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Antibiotics after abscess surgery may cut fistula risk, but more study needed
Disease control CompletedThis study tested whether giving antibiotics after draining a perianal abscess can prevent a painful complication called a fistula. It included 15 adults who had abscess surgery. The main goal was to see if a larger trial is possible, not to prove the treatment works.
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Exercise plus brain zaps may sharpen memory in Alzheimer's
Symptom relief CompletedThis study tested whether combining exercise with a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can improve memory in 60 adults aged 50 and older with mild cognitive impairment or Alzheimer's disease. Participants exercised while recei…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Apr 30, 2026 15:52 UTC
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Coffee may speed up gut recovery after surgery, study finds
Symptom relief CompletedThis study looked at whether drinking coffee after abdominal surgery helps the gut start working again sooner. 174 adults who had surgery were given either regular coffee, decaf coffee, or warm water three times a day. The goal was to see if coffee could reduce common problems li…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Ice packs after surgery: simple cold therapy may ease pain and speed recovery
Symptom relief CompletedThis study looked at whether applying ice packs to surgical cuts every 4 hours for 3 days helps adults recover after chest, belly, or groin surgery. 196 patients took part, and the main goal was to see if a larger study is possible. The researchers measured pain, recovery quality…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Apr 29, 2026 15:15 UTC
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New device tracks breathing during cardiac arrest resuscitation
Knowledge-focused CompletedThis study tested whether a device that gives real-time feedback on breathing quality can help paramedics during cardiac arrest. Researchers compared ventilation before and after using the Zoll Accuvent device in 412 adults. The goal was to see if the device improves breathing ra…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated May 01, 2026 18:42 UTC
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New scan could sharpen brain tumor targeting
Knowledge-focused CompletedThis study tested whether a special type of scan (FET-PET/MRI) can better show the full extent of glioblastoma brain tumors after surgery compared to standard MRI. The goal was to see if this could help doctors plan radiation treatment more accurately. Eleven adults who had surge…
Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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New dosing study aims to cut blood loss in joint replacements
Knowledge-focused CompletedThis study tested different doses of tranexamic acid (TXA) to find the best amount to give during hip or knee replacement surgery. TXA helps reduce bleeding and the need for blood transfusions. Researchers measured TXA levels in the blood of 21 adults to build a model for future …
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC