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Memory boost? exercise plus brain stimulation shows promise

NCT ID NCT03670615

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This pilot study tested whether combining exercise with a gentle brain stimulation technique called tDCS could improve memory in 60 older adults with mild cognitive impairment or Alzheimer's disease. Participants exercised and received either real or sham brain stimulation. The goal was to see if the combo helps word recall and recognition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M3H0A7, Canada

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS) and exercise

What this could lead to

If it works, this could point toward a non-drug way to help memory in people with early Alzheimer's or mild cognitive impairment.

What could go wrong

This is a small pilot study (60 people) with no phase, so results are very early. The memory benefits may be small or not last long, and tDCS can cause mild scalp discomfort.

Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.