Samsung Medical Center

This study looks at whether people who have had a heart attack but do not have heart failure can safely stop taking beta-blockers after at least one year of treatment. About 2,540 adults will be randomly assigned to either stop or continue the medication. The goal is to see if st…

This study tests a new drug, selinexor, combined with standard chemotherapy for people with B-cell lymphoma that has returned or not responded to treatment and has spread to the brain or spinal cord. The goal is to see if the combination is safe and effective. About 37 adults wil…

This phase 2 trial tests whether adding tepotinib to lazertinib can shrink tumors in people with a specific type of advanced lung cancer (EGFR-mutant NSCLC) that stopped responding to lazertinib alone due to MET gene changes. About 47 participants will receive the combination the…

This study compares a newer pacing method (left bundle branch area pacing) to the standard method (right ventricular pacing) in 200 patients with heart block and normal heart function. The goal is to see if the newer method better preserves heart pumping ability and reduces compl…

This study compares two drug combinations—aspirin plus prasugrel versus aspirin plus clopidogrel—in 3,500 adults with complex coronary artery disease who are getting stents. The goal is to see which combo better prevents major heart problems like death, heart attack, or stent blo…

This study tests a shorter course of radiation therapy combined with chemotherapy for people with cervical cancer. Standard treatment takes 7-8 weeks, but this approach aims to finish faster while still controlling the tumor. The trial will measure tumor shrinkage and track side …

This study tests whether a smart board device can help people with brain disorders improve arm function at home. It involves 40 adults with arm weakness lasting over 3 months. Participants will either use the smart board or do standard home exercises, and researchers will compare…

This study is for men whose prostate cancer has returned after surgery, shown by rising PSA levels. It compares a standard 4-week radiation course to a much shorter 1-2 week course. The goal is to see if the shorter option is just as effective at controlling the cancer while bein…

This study tests whether giving a maintenance immunotherapy drug (avelumab) after standard chemotherapy can help prevent upper tract urothelial cancer from coming back. About 48 adults who have already completed chemo and show no signs of cancer will receive avelumab every two we…

This study tests whether adding a special type of radiation (adaptive pulse radiotherapy) to standard immunotherapy can help people with advanced solid tumors. About 35 participants will receive their usual immunotherapy plus 2-3 high-dose radiation sessions. Researchers will che…

This study looks at 408 adults with severe heart failure (cardiogenic shock) who need a heart-lung machine (ECMO) and have kidney injury. It compares starting kidney dialysis early versus waiting for standard timing. The goal is to see which approach reduces the chance of death o…

This study compares a new AI-driven method that analyzes angiogram images to a standard invasive test that uses a pressure wire inside the heart artery. Both tests help doctors decide if a stent is needed. About 2,100 adults with coronary artery disease will be randomly assigned …

This study tests a smartphone app that provides exercise and education for people recovering from rotator cuff repair surgery. The goal is to see if the app improves shoulder function and reduces pain better than standard care. About 70 adults who have had this surgery will use t…

This study tests whether a smart glove can help people with brain disorders (like stroke or brain injury) improve arm and hand function from home. Forty adults with weakness on one side for at least 3 months will either use the smart glove or do standard home exercises. The goal …

This study tests whether personalized brain stimulation (rTMS) can improve arm movement in people who had a stroke within the past 3 months. Researchers will tailor the treatment based on each patient's remaining brain function, rather than using a one-size-fits-all approach. Abo…

This study tests a personalized form of brain stimulation (rTMS) to help people with Parkinson's disease walk better. Instead of using the same stimulation for everyone, the treatment is tailored to each patient's brain function. The study will enroll 60 participants and compare …

This study looks at whether a special type of PET-CT scan can better predict how well treatment is working in people with advanced breast cancer compared to standard imaging. About 100 adults starting their first treatment will be followed for 48 weeks. The goal is to improve how…

This study looks at whether using a special heart CT scan (coronary CT angiography) for follow-up is better than usual care for high-risk patients who have had a stent placed. About 3,500 adults will be tracked to see which approach reduces the chance of major heart problems like…

This study is looking at whether the kind of anesthesia used during surgery for non-small cell lung cancer can affect how long people stay cancer-free. About 5,384 people having lung cancer surgery will be randomly assigned to receive either inhaled gas anesthesia or propofol-bas…

This study looks at whether CT scans can help predict which patients with non-small cell lung cancer will benefit from chemoimmunotherapy before surgery. Researchers will compare CT images taken before and after treatment with actual results from surgery. The goal is to develop a…

This study looks at 200 adults with sick sinus syndrome who need a pacemaker. Researchers want to see if pacing the heart from a spot called Bachmann's bundle is better for heart health than the usual spot, the right atrial appendage. Participants will be followed with heart ultr…

This study is creating a huge, organized database of up to 800,000 Korean patients with heart or brain blood vessel diseases. Researchers will collect medical history and follow patients over many years to track their health outcomes. The goal is to identify patterns and risk fac…

This study aims to find genetic markers in tissue and blood that can help diagnose early stomach cancer and precancerous growths, and predict if the cancer will come back after treatment. Researchers will analyze samples from 1,730 adults with these conditions. The goal is to imp…

This study is collecting medical information and tissue samples from 350 head and neck cancer patients each year at Samsung Medical Center. Researchers want to understand why some patients respond better to treatment than others. The goal is to find clues (biomarkers) that could …