Samsung Medical Center

This early study tests a single dose of stem cells (PNEUMOSTEM®) given into the windpipe of very premature babies with high blood pressure in their lungs. The goal is to see if it is safe and might improve breathing, reduce time on a ventilator, and lower the need for oxygen. Onl…

This study compares a moderate statin (pitavastatin) combined with ezetimibe against high-intensity statins (atorvastatin or rosuvastatin) in patients aged 75+ with coronary artery disease who need a stent. The goal is to see if the combo is just as good at preventing heart attac…

This study looks at whether feeding through the gut (enteral nutrition) or through a vein (parenteral nutrition) leads to better outcomes for critically ill adults recovering from shock in the ICU. About 1,150 patients will be randomly assigned to one of the two feeding methods. …

This study tests a drug called tislelizumab in about 72 adults with advanced solid tumors that no longer respond to standard treatments. Only patients with a specific gene signature (T cell inflamed GEP score) are eligible. The drug is given every three weeks to see if it can shr…

This study looks at 5000 heart attack patients who had a procedure to open blocked arteries and are taking two blood thinners. It compares giving everyone a strong stomach acid blocker versus using a standard approach to prevent stomach bleeding. The goal is to see which strategy…

This study tests whether routinely placing a small tube (catheter) in the leg can prevent serious limb complications in patients on a heart-pump machine. About 500 adults with severe heart failure or shock will be randomly assigned to get the tube placed right away or only if nee…

This study tests a new way to find a hidden heart condition called cardiac amyloidosis in people with atrial fibrillation (AF). Researchers will use AI to analyze EKGs and CT scans to spot early signs of the disease. About 500 adults with AF and certain warning signs will be spli…

This study will observe how often children in pediatric intensive care units (PICUs) receive physical or occupational therapy as part of their routine care. Researchers will track 396 children aged 18 or younger who have been in the PICU for at least 72 hours. The goal is to unde…

This observational study will follow 20,000 Korean adults who have had a heart attack. Researchers will collect data from hospitals across Korea to understand what affects long-term survival and to develop a risk model specific to Korean patients. The goal is to improve treatment…

This study looks at how different ventilator pressure settings affect lung pressure and blood flow in COPD patients undergoing lung surgery. Forty-eight participants will each try three short-term settings in random order. The goal is to find which setting keeps the lungs and hea…

This study will analyze medical records from 100,000 people in Korea who had early-stage hormone receptor-positive, HER2-negative breast cancer and received surgery followed by other treatments. The goal is to see how often the cancer comes back and what factors might affect that…

This study looks at whether a special blood filter called Oxiris can help people with sepsis-related kidney injury. Sepsis causes inflammation that can damage kidneys, and this filter is designed to remove harmful substances from the blood. Researchers will compare the Oxiris fil…

This study looks at whether developing insomnia after a heart attack and related heart procedures (like stents or bypass surgery) is linked to worse long-term outcomes, such as death, another heart attack, or stroke. Researchers will analyze a large Korean health database to find…

This study tests two types of robot conversations—simple rule-based chats and smarter AI-powered chats—to see which one helps hospitalized children aged 2-9 feel more engaged and comfortable. About 60 kids will interact with a robot named LIKU during emotional support and safety …