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Anesthesia choice may impact lung cancer return

NCT ID NCT06330038

First seen Apr 30, 2026 · Last updated Jun 19, 2026 · Updated 8 times

Summary

This study compares two types of anesthesia—propofol-based intravenous anesthesia versus inhaled gas anesthesia—in over 5,300 people having surgery for early-stage non-small cell lung cancer. The goal is to see if one method leads to a longer time before the cancer comes back. Participants will be randomly assigned to one anesthesia type and followed for recurrence and survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propofol and inhaled anesthetics (sevoflurane, desflurane, isoflurane)

What this could lead to

If it works, this could show that choosing propofol anesthesia over gas anesthesia helps prevent lung cancer from coming back after surgery.

What could go wrong

This is a large phase 4 trial, but the effect of anesthesia on cancer recurrence is still debated and unproven. Results may show no difference or be influenced by other factors.

Conditions

The condition(s) this trial relates to.

lung neoplasm Neoplasm Metastasis non-small cell lung carcinoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.