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New study tests simpler procedure for stomach precancer

NCT ID NCT07161479

Disease control Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two endoscopic procedures—argon plasma coagulation (APC) and endoscopic mucosal resection (EMR)—for treating small (1 cm or smaller) precancerous growths in the stomach called gastric adenomas with low-grade dysplasia. About 160 adults will be randomly assigned to receive either APC or EMR. The main goal is to see if APC is as effective as EMR at preventing the growth from coming back, while possibly being safer and faster.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Argon plasma coagulation (APC) and endoscopic mucosal resection (EMR) are both procedures used to remove precancerous growths in the stomach.
What this could lead to
If APC works as well as EMR, it could offer a simpler, safer, and cheaper option for treating small precancerous stomach growths.
What could go wrong
This is a relatively small trial (160 people) and results may not apply to larger or more advanced growths. APC does not provide a tissue sample, so there is a risk of incomplete removal or recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 160 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 20 years or older * Diagnosed with gastric adenoma with low-grade dysplasia measuring ≤ 1 cm on endoscopy * Scheduled to undergo endoscopic treatment * Able and willing to provide written informed consent Exclusion Criteria: * Previous treatment for gastric adenoma or gastric cancer * History of gastrectomy * Diagnosis of gastric cancer or high-grade dysplasia at the time of enrollment * Presence of multiple gastric adenomas * Pregnant, breastfeeding, or possibility of pregnancy * Uncontrolled chronic illnesses that may interfere with trial participation (e.g., uncontrolled hypertension, uncontrolled diabetes, chronic kidney disease, ascites, heart failure, psychiatric disorders)

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Conditions

The condition(s) this trial relates to.

gastric adenoma gastric neoplasm precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dysplasia stomach Gastric adenoma Precancerous conditions Stomach neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kangbuk Samsung hospital

    RECRUITING

    Seoul, 03181, South Korea

  • National Cancer Center

    RECRUITING

    Goyang-si, 10408, South Korea

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

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