Rush University Medical Center

This study tests whether giving multiple doses of tranexamic acid (TXA) by mouth or through a vein reduces blood loss and the need for blood transfusions after spine surgery better than a single dose. It involves 604 adults scheduled for open back surgery who are at high risk for…

This study tests whether using a special computer tool (Ablation Index) can make a heart procedure faster and more effective for people with a history of heart attack and a dangerous fast heartbeat called ventricular tachycardia. About 100 adults with ischemic cardiomyopathy will…

This study compares a team-based program that combines medical care and social support to standard care for controlling high blood pressure. It will enroll 200 African American and Latinx adults with uncontrolled hypertension. The main goal is to see if more participants lower th…

This study looks at whether encouraging people to take part in enjoyable recreational activities can help them make healthier choices and lower their risk for heart disease, diabetes, and stroke. Researchers will track 120 adults' health habits and offer some a 6-month program pr…

This study tests a 12-month church-based program to help African Americans with uncontrolled high blood pressure lower their numbers. Participants will have their blood pressure checked and learn about healthy eating and taking medications as prescribed. The goal is to see if a c…

This study tests a pharmacist-led program to help adults with uncontrolled high blood pressure in underserved Chicago communities. Over 3 months, a mobile team provides blood pressure checks, medication management, and health education. The goal is to lower blood pressure and imp…

This study tests a self-management program for people with COPD to see which parts work best to reduce hospital stays and improve daily life. Researchers will enroll 448 adults aged 40+ who have had a COPD-related hospitalization in the past year. Participants will use a smartpho…

This study tests whether treating PTSD symptoms can prevent acute pain (like from an injury) from becoming long-term chronic pain. Researchers will use either a nerve block procedure or talk therapy to reduce PTSD in 345 adults. The goal is to see if lowering PTSD symptoms helps …

This study compares two knee braces used after ACL reconstruction surgery: the new KRONOS brace and the standard Breg T-Scope brace. The goal is to see which brace reduces pain and helps the knee straighten better during recovery. About 40 adults having their first ACL surgery wi…

This study compares two different vibrating devices designed to help people who have trouble clearing mucus from their airways. Researchers want to see which device works better at removing secretions and improving breathing. The study will involve 64 adults with a high need for …

This study compares two knee braces for people with knee osteoarthritis that affects the inner part of the knee. Researchers want to see if the braces reduce pain during walking and improve how the knee moves. About 30 adults aged 40-85 with moderate knee pain will wear a brace f…

This study tests whether a computer-based training program can help people with Huntington's disease better understand others' emotions and social cues. Twenty participants will use the program at home and provide feedback on its ease and usefulness. The goal is to see if this ap…

This study compares two methods to break up large or hard-to-remove stones in the bile or pancreatic ducts: a low-power laser and a shock-wave device. About 40 adults will be randomly assigned to one of the two treatments during an ERCP procedure. The goal is to see which method …

This study tests a single infusion of a new drug called (2R,6R)-HNK to see if it can reduce nerve pain in the arms or legs. About 25 adults with chronic nerve pain will receive the drug, ketamine, or a placebo in random order, with five weeks between each treatment. Researchers w…

This study tests whether a special nerve monitoring device (NeuroVision) can prevent nerve injuries better than standard monitoring during spine surgery. About 148 adults having lateral spine surgery will be randomly assigned to one of the two monitoring methods. The main goal is…

This study looks at whether ICU doctors and nurses make better predictions about a patient's chance of surviving one year when they are given a special risk score called ProVent-14. The score uses simple medical information collected after 14 days on a breathing machine. About 23…

This study looks at whether showing people a live ultrasound of their heart in the emergency room can motivate them to eat better, exercise more, and see a doctor regularly. Adults aged 45 and older with high blood pressure, diabetes, or obesity are eligible. Participants either …

This study looks at why people from lower-income backgrounds often have less success in weight loss programs. Researchers will track daily experiences and decision-making patterns in 230 adults with obesity. The goal is to understand how stress and thinking habits affect weight l…

This study looks at whether the time of day a breathing test is done affects how quickly ICU patients can stop using a ventilator. About 348 adults who have been on a ventilator for more than two days will be split into two groups: one gets the test early in the morning, the othe…