Knee brace showdown: which one helps arthritis sufferers walk better?
NCT ID NCT07224958
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two knee braces for people with knee arthritis affecting the inner part of the knee. Researchers will measure changes in pain and walking ability over 8 weeks. Participants must be 40-85 years old, have moderate pain, and be willing to wear the brace at least 4 hours a day.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Inclusion Criteria: * Age 40-85 years. * BMI ≤ 35. * Physician-diagnosed medial compartment knee osteoarthritis. * Visual Analog Scale (VAS) walking pain ≥ 4. * Willing to wear assigned brace ≥ 4 hours/day. * Able to walk independently for 20 minutes unaided. * Stable pain medication regimen ≥ 4 weeks. * ≥3 months since last hyaluronic acid (HA), platelet-rich plasma (PRP), or steroid injection. Exclusion Criteria: * Lateral or patellofemoral osteoarthritis. * Prior knee replacement. * Significant ligament injury or acute lower limb injury. * Neurological condition affecting gait. * Severe psychiatric or neurological disorder affecting pain perception. * Skin condition or allergy preventing brace use. * Current use of another brace or assistive device. * Recent opioid or corticosteroid use (\<4 weeks). * Pregnant. Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
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