New hope for nerve pain: experimental drug shows promise in early trial

NCT ID NCT05864053

Recruiting now Symptom relief Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 25, 2026 · Updated 17 times

Summary

This study tests a single infusion of a new drug called (2R,6R)-HNK to see if it can reduce nerve pain in the arms or legs. About 25 adults with chronic nerve pain will receive the drug, ketamine, or a placebo in random order, with five weeks between each treatment. Researchers will measure pain levels, daily function, and sleep quality for up to 35 days after each infusion.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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PAIN, NEUROPATHIC