Ruijin Hospital

This study looked at 275 people with pemphigus, a serious skin condition that causes blisters. Researchers compared different doses of the drug rituximab to see which worked best and had the fewest side effects. The goal was to control the disease and reduce the need for steroids…

This early study tested a single injection of HM2002, a circular RNA, given directly into the heart muscle during bypass surgery in 3 people with ischemic heart failure. The main goal was to check safety and tolerability. This is a first-in-human trial, not a cure, and participan…

This study tested a new treatment for people with pancreatic cancer that spread only to the liver, after their first chemotherapy stopped working. The treatment delivers two chemotherapy drugs directly to the liver through a thin tube, followed by more chemo either through the tu…

This study compared robotic surgery to traditional open surgery for removing tumors in the pancreas and nearby areas. 268 patients took part to see which method led to faster recovery after the operation. The goal was to find out if robotic surgery is as good as or better than op…

This study tested two different spots in the brain for deep brain stimulation to control tremors in people with Parkinson's disease. 27 participants received stimulation in both the posterior subthalamic area and the subthalamic nucleus to see which worked better. The goal was to…

This study tested a drug called telitacicept in 20 adults with antiphospholipid syndrome (APS), a condition where the immune system mistakenly attacks healthy cells, raising the risk of dangerous blood clots. The goal was to see if the drug could lower levels of harmful antibodie…

This study tested a new type of PET scan that looks for a protein called alpha-synuclein in the brain, which is linked to Parkinson's disease, multiple system atrophy, and a sleep disorder that often leads to Parkinson's. Researchers scanned 55 people, including healthy volunteer…

This study looked at 332 people with low-risk papillary thyroid cancer that had spread to lymph nodes in the neck. Researchers compared robotic surgery (using small cuts under the arms and around the breasts) to standard open surgery. They wanted to see if the robotic method remo…

This study tested whether combining repetitive transcranial magnetic stimulation (rTMS) with motor training improves arm function in stroke patients. 60 adults with upper limb weakness after a stroke received either online rTMS (during training), offline rTMS (before training), o…

This study tested a new method to measure lung blood flow using electrical impedance tomography (EIT) that does not require patients to hold their breath. 24 adults on breathing support (like nasal cannula or high-flow oxygen) took part. The goal was to see if the new method give…

This study tested a bedside imaging method called electrical impedance tomography (EIT) to see how different ventilator pressure levels affect lung function in 120 adults with ARDS, a severe lung injury. The goal was to identify which patients respond best to higher pressures and…

This study tested a new way to predict if patients with acute respiratory failure can safely stop using a breathing machine. Researchers used a non-invasive imaging technique called electrical impedance tomography (EIT) to measure how well the lungs fill with air during a breathi…

This study looked at 375 patients having surgery to remove small lung nodules. It compared a new method that uses one breathing tube throughout the procedure versus the standard method that switches tubes. The goal was to see if the simpler method is just as safe and effective.