Roswell Park Cancer Institute
Clinical trials sponsored by Roswell Park Cancer Institute, explained in plain language.
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First-in-Human cancer vaccine trial seeks to train immune system to fight rare tumors
Disease control CompletedThis early-stage study tested the safety and immune effects of a new cancer vaccine called SurVaxM in 19 patients with advanced neuroendocrine tumors that had spread. The vaccine aims to teach the body's immune system to recognize and attack cancer cells by targeting a protein ca…
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 03, 2026 19:55 UTC
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Doctors test light meter to guide cancer treatment during surgery
Disease control CompletedThis early-phase study tested whether a light measurement system could safely guide a special cancer treatment during surgery. The treatment involves giving patients a light-sensitive drug, then using laser light during surgery to activate it against cancer cells in the chest lin…
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Double attack on advanced liver cancer shows promise
Disease control CompletedThis study tested whether using two drugs together works better than one for treating advanced liver cancer that has spread. The trial combined sorafenib, a pill that blocks cancer cell growth, with pembrolizumab, an IV drug that helps the immune system fight cancer. It involved …
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New drug cocktail aims to slow advanced colon cancer
Disease control CompletedThis study tested whether combining three existing cancer drugs works better to control advanced colorectal cancer that has spread or cannot be removed by surgery. The trial involved 42 patients whose cancer had progressed despite prior treatments. Researchers aimed to see if thi…
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Early trial tests Four-Drug combo to train immune system against blood cancers
Disease control CompletedThis early-stage study tested a combination of a cancer vaccine, chemotherapy, and immunotherapy in 8 patients with certain high-risk blood cancers. The main goal was to check the safety of this four-drug approach and see if it could help the body's immune system better target an…
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New device aims to catch chemotherapy leaks before they harm patients
Disease control CompletedThis study tested whether a small sensor called ivWatch could detect when IV fluids or medications leak from a vein into surrounding tissue during cancer treatment. The research involved 2,400 adult cancer patients receiving chemotherapy through a standard IV line. The goal was t…
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Scientists test how nicotine 'Salts' in vapes hit your bloodstream
Knowledge-focused CompletedThis study aimed to understand how nicotine from two different types of vaping liquid—'salt-based' and 'free-base'—gets into the bloodstream and affects users. Researchers had 15 daily vapers try four different e-liquids to measure nicotine levels in their blood and ask about the…
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC