Roswell Park Cancer Institute

This study tested a combination of two drugs, sorafenib and pembrolizumab, in 37 adults with advanced liver cancer that had spread. The goal was to see if the combination could shrink tumors or slow cancer growth. The approach uses sorafenib to block cancer cell growth and pembro…

This early-phase study tested a light-measuring system used during surgery to treat mesothelioma, non-small cell lung cancer, or other cancers that spread to the lining of the lungs. Nine participants received a light-activated drug called porfimer sodium, and doctors used the sy…

This early-phase trial tested a mix of a cancer vaccine, chemotherapy, and immunotherapy in 8 people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) with low blast counts. The goal was to see if the combination is safe and helps the immune system fight cancer …

This study tested a combination of three drugs (TAS-102, irinotecan, and bevacizumab) in 42 people with advanced colorectal cancer that had already been treated before. The goal was to see if this mix could slow or stop cancer growth better than standard options. Participants rec…

This early-phase trial tested a vaccine called SurVaxM in 19 people with neuroendocrine tumors that had spread. The vaccine is designed to teach the body's immune cells to recognize and attack tumor cells. The main goal was to check for side effects and see if the vaccine could c…

This study tested a device called ivWatch® on 2,400 cancer patients getting chemotherapy through a vein. The device watches for fluid leaking out of the vein, which can damage skin and tissue. The goal was to see if it could spot leaks earlier than a nurse could. If successful, i…

This early-phase study tested a vaccine called CIMAvax-EGF in 20 people at high risk for lung cancer or survivors at risk of recurrence. The vaccine works by helping the body make antibodies against a protein that can fuel cancer growth. Researchers checked safety, immune respons…

This study looked at whether adding the antidepressant venlafaxine to standard pain medicines (gabapentin, methadone, oxycodone) can better control pain and improve quality of life in people with head and neck cancer receiving chemoradiation. About 62 patients took part. The goal…

This early-phase study tested a treatment for people with advanced lung cancer that blocks the airways. Doctors injected a light-sensitive drug into the blood, then used a laser to activate it inside the tumor, aiming to shrink it and relieve symptoms. The study included 19 adult…

This study looked at how nicotine salt-based vaping products deliver nicotine into the blood compared to regular free-base nicotine e-liquids. Fifteen daily vapers took part, and researchers measured nicotine levels, harshness, and satisfaction. The goal was to understand the abu…

This study looked at how the hormone therapy tamoxifen affects breast cancer tumors. Researchers examined the interaction between estrogen receptors and a protein called p53 in tumor samples from 59 patients. The goal was to learn more about why some patients respond to tamoxifen…