Roswell Park Cancer Institute

This early-phase trial tested whether adding decitabine/cedazuridine to enzalutamide could help men with metastatic castration-resistant prostate cancer whose cancer had stopped responding to enzalutamide alone. Only 8 men participated before the study was stopped. The main goals…

This early-phase trial tested whether combining two immune-boosting drugs, rintatolimod and interferon alpha-2b, could help cancer patients clear COVID-19. Only 4 patients enrolled before the study was terminated. The goal was to find a safe dose and see if the treatment could re…

This study tested a new combination treatment for people with advanced melanoma that stopped responding to standard immunotherapy. The approach used special immune cells (aDC1) plus drugs to boost the immune system and reduce pain. Only one person enrolled before the study was st…

This early-phase study tested a treatment that uses a light-activated drug (photodynamic therapy) plus immunotherapy to fight non-small cell lung cancer with pleural spread or malignant pleural mesothelioma. Only 5 people took part before the study ended early. The main goal was …

This study explored new ways to measure and manage pain in cancer patients and survivors. Researchers used a non-invasive brain imaging technique (fNIRS) to see how the brain reacts to pain and tested whether virtual reality (VR) could help reduce pain and the need for pain medic…

This study looked at how well daily vapers and experts can identify and detect flavors in e-liquids. Researchers tested people's ability to recognize different flavor concentrations and mixtures. The goal was to understand how consumers perceive e-liquid flavors compared to train…

This study looked at giving a very precise, high-dose radiation treatment (SBRT) before surgery for people with stage I to IIIA non-small cell lung cancer. The goal was to see if this combination is safe and how it affects survival. The study was stopped early, but it included 20…

This study looked at how different vape flavors and types of nicotine (synthetic vs. tobacco-derived) change the way people puff. Researchers measured puff count, duration, and volume in 21 daily vapers. The goal was to understand how these factors influence vaping behavior and p…