National Institutes Of Health Clinical Center (cc)

This study tests a new dengue vaccine in 127 healthy adults aged 18 to 59. Researchers want to see how safe the vaccine is and how the immune system responds, especially in people who have had dengue before. Participants receive one shot and are closely monitored for side effects…

This study looks at whether a blood test called MCV can help guide phlebotomy (blood removal) therapy for people with hereditary hemochromatosis, a genetic condition causing too much iron absorption. About 622 participants aged 15 and older will have regular blood draws to lower …

This study looks at whether a newer antibiotic called cefiderocol can save more lives than current treatments for a dangerous, drug-resistant bacteria (CRAB). Researchers will compare death rates in 5,000 hospitalized adults over 28 days. The goal is to find a better way to contr…

This study tests a laser device that destroys prostate cancer tumors using heat, guided by ultrasound instead of MRI. About 30 men with low- to intermediate-risk prostate cancer that hasn't spread will receive this focal treatment. The goal is to see if it's safe and effective at…

This study looks at whether a 10-week exercise program can help adults aged 18 to 80 who still have symptoms after a COVID-19 infection. Participants will do cardio exercise three times a week and attend weekly education classes. The goal is to see if exercise improves physical c…

This study looks at how healthy lungs respond to a substance that mimics a bacterial infection. Researchers will collect lung cells and fluids from 58 healthy non-smoking adults to study inflammation and tiny molecules called microRNA. The goal is to better understand the body's …

This study aims to create computer programs that can help doctors detect and diagnose diseases from medical images like CT scans and MRIs. Researchers will analyze over 144,000 existing images from patients of all ages taken since 1953. The goal is to make radiology faster and mo…

This study aims to describe how assisted suicide is practiced in Switzerland by analyzing interviews with 25 Swiss experts, including doctors, academics, and representatives from right-to-die societies. The researchers will examine the ethical, legal, and medical aspects of the p…

This study tests a special needle with a tiny tracking device inside, like a mini GPS, to help doctors find hard-to-see tumors during biopsies or ablation procedures. About 3,900 adults with certain cancers or growths will take part. The goal is to see if this tool can place the …

This study creates a registry to collect information about pregnancies and births among people who took part in NIH clinical trials. It includes up to 500 participants of any age who became pregnant while in a study or within one year after. Researchers will interview participant…

This study aimed to see if a virtual education program could help teenagers and young adults with congenital adrenal hyperplasia (CAH) learn to manage their own health care as they move from pediatric to adult doctors. It planned to enroll 16- to 22-year-olds already in a related…

This study watches how the trillions of bacteria living in and on our bodies change when someone stays in the hospital. Researchers will take daily swabs from the skin, throat, and rectal area, plus stool samples, from 250 patients aged 2 and older. The goal is to learn which ger…