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Laser or freezing: a gentler approach to prostate cancer?

NCT ID NCT02759744

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This pilot study is testing a device that uses ultrasound images to guide a laser or freezing probe directly into prostate tumors. The goal is to destroy only the cancerous tissue while sparing healthy areas. Thirty men with low- to intermediate-risk prostate cancer that hasn't spread will be treated and followed for three years to see if the approach is safe and practical.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

laser ablation or cryotherapy device

What this could lead to

If successful, this could offer a less invasive, outpatient-like treatment for low-risk prostate cancer, potentially reducing side effects compared to surgery or radiation.

What could go wrong

This is a very small pilot study (30 men) focused on feasibility, not effectiveness. The treatment may not fully destroy the tumor, and long-term outcomes are unknown.

Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.