Mahidol University

This study compares two devices used with a facemask to widen the upper jaw in children aged 8–12 who have an underbite (skeletal Class III) and a narrow upper jaw. One device is the Invisalign Palatal Expander (IPE), and the other is the Rapid Palatal Expander (RPE). Researchers…

This study tests whether giving human albumin (a natural blood protein) along with standard care can help more people survive surgical septic shock, a life-threatening infection complication. About 304 adults in the surgical ICU will be randomly assigned to receive either standar…

This study tests whether aminophylline, a drug usually used for asthma, can prevent kidney damage in children receiving cisplatin chemotherapy. About 24 children under 18 will receive either aminophylline or a placebo alongside their standard hydration protocol. Researchers will …

This study tests whether a sleep medication called lemborexant can help older adults (65+) in the intensive care unit sleep better and avoid delirium—a state of sudden confusion common in the ICU. One hundred patients will receive either the drug or a placebo for three nights, al…

This study looks at whether mild electrical brain stimulation, combined with physical therapy and walking exercises, can improve brain function in people who had a stroke. Researchers will measure changes in brain blood flow using a special light-based scanner. The goal is to und…

This study looks at how two common treatments for septic shock—intravenous fluids and blood pressure-raising medications (vasopressors)—change the heart's pumping ability. Researchers will use echocardiograms (heart ultrasounds) before and after treatment in 180 adults with septi…

This study aims to translate and test a Thai version of a questionnaire that measures how well children recover after surgery. Researchers will include 130 children aged 2-17 undergoing elective surgery at Siriraj Hospital. The goal is to create a reliable tool for doctors and fa…