Mahidol University

This study tests whether the drug aminophylline can protect the kidneys of children receiving cisplatin chemotherapy. Twenty-four children will be randomly assigned to receive either aminophylline or a placebo alongside their standard chemo hydration. Researchers will measure kid…

This study tests whether giving extra human albumin—a natural blood protein—along with standard care can help people survive septic shock after surgery. Septic shock is a life-threatening condition where infection causes dangerously low blood pressure. The trial will enroll 304 a…

This study compares two treatments for adults with streptococcal bacteria in their bloodstream. One group gets standard beta-lactam antibiotics plus a placebo, while the other gets standard antibiotics plus levofloxacin. Researchers will track whether the combination reduces comp…

This study compares the Invisalign Palatal Expander (IPE) with the Rapid Palatal Expander (RPE) in children aged 8–12 who have a narrow upper jaw and an underbite (skeletal Class III). Participants will wear a facemask after expansion. Researchers use 3D X-rays to measure changes…

This study tests whether adding stem cells from donated placentas to standard cooling therapy can improve outcomes for newborns with brain injury caused by lack of oxygen at birth. About 40 infants with moderate to severe injury will receive either stem cells or a placebo within …

This study tests two non-invasive treatments for plantar fasciitis, a common cause of heel pain. 28 adults will receive either high-intensity laser therapy or focused shock wave therapy, plus exercises. Researchers will measure pain and foot function over 12 weeks to see which wo…

This study tests whether a greater occipital nerve block (an injection near the back of the head) can help people with migraine who overuse painkillers. About 130 participants will receive either the nerve block or a placebo. The goal is to see if the injection reduces headache d…

This study tests whether a 14-day course of the antibiotic rifaximin can reduce bothersome bloating in adults with irritable bowel syndrome, functional constipation, or similar gut disorders. About 78 participants will receive either rifaximin or a placebo, and researchers will m…

This study tests whether a computer-based stepping game, called Smart±step, can help older adults with mild cognitive impairment (MCI) improve their balance, thinking, and quality of life while reducing their risk of falling. About 70 participants will use the game, which combine…

This study tests a new care program for older adults in Thailand who have had a heart attack. The program combines in-person education, motivational counseling, and a mobile app to help them adopt healthy habits and track their recovery. Researchers will measure if this approach …

This study tests whether a sleep medication called lemborexant can help older adults in the intensive care unit (ICU) sleep better and reduce their risk of delirium, a state of sudden confusion. The trial will involve 100 patients aged 65 and older who are in the surgical ICU. Pa…

This study looks at how the amount of deep sleep just before waking affects how alert people feel after a 2-hour nap taken at night. Researchers will monitor brain activity during sleep and test reaction times after waking. The goal is to understand sleep inertia and improve nap …

This study tests whether a simple brain activity monitor (BIS) can predict how well critically ill patients with decreased consciousness will do. Researchers will compare BIS readings from 40 ICU patients—half with very low consciousness and half more alert—and track their hospit…

This study is creating a new questionnaire to measure how well children recover after anesthesia and surgery. Researchers will work with 200 children aged 2-17 and their parents to develop and test the tool. The goal is to provide a simple, child-friendly way to assess recovery q…

This study looks at how mild electrical brain stimulation (tDCS or tACS) combined with physical therapy affects brain activity in stroke survivors. 60 adults who had a stroke 2 weeks to 5 years ago will take part. The goal is to measure changes in blood oxygen levels in the brain…

This study watches how the heart responds to two common treatments for septic shock: intravenous fluids and blood-pressure-raising medications (vasopressors). Researchers will use echocardiograms (heart ultrasounds) before and after treatment in 180 adults. The goal is to see whi…