Kidney shield? drug may protect young cancer patients from chemo harm
NCT ID NCT06196853
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 34 times
Summary
This study tests whether the drug aminophylline can protect the kidneys of children receiving cisplatin chemotherapy. Twenty-four children will be randomly assigned to receive either aminophylline or a placebo alongside their standard chemo hydration. Researchers will measure kidney function and damage markers over five days to see if aminophylline helps.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Siriraj hospital, Mahidol university
Bangkok, 10700, Thailand
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
aminophylline
What this could lead to
If it works, this could point toward a way to reduce kidney damage in children undergoing cisplatin chemotherapy.
What could go wrong
This is a very small, early-phase trial with only 24 children, so results may not be conclusive. Aminophylline can cause side effects like nausea, vomiting, and heart rhythm changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.