Maastricht University Medical Center

This study compares two methods of breast reconstruction in women who had a mastectomy and radiation for breast cancer: autologous fat transfer (AFT) and DIEP flap surgery. About 280 participants will be randomly assigned to one of the two procedures. The main goal is to see if A…

This study tests whether setting a personalized 'optimal' blood pressure for each patient with severe traumatic brain injury reduces brain damage compared to standard fixed targets. Researchers will enroll 60 adults in the ICU and measure brain injury markers in the blood over fi…

This study tests a drug called tarlatamab in 35 adults with small cell lung cancer that has spread to the brain but is not causing symptoms. The goal is to see if the drug can shrink or control these brain tumors. Participants must have already had standard chemotherapy and be in…

This study looks at whether eating 50 grams of walnuts every day for 24 weeks can improve brain function in adults aged 45-75 with abdominal obesity. Researchers will measure blood flow in the brain and how well the brain responds to insulin, as well as thinking skills and appeti…

This study tests whether plant sterols, found in some foods, change how a newly discovered protein called cholesin works. Cholesin is released from the gut after eating cholesterol and tells the liver to make less cholesterol. Researchers will give 23 healthy adults three differe…

This observational study will follow 600 adults with chronic or acute heart failure to see how biomarkers and other factors predict individual responses to standard medications. Participants will have assessments at the start and after 1, 3, and 6 months, with follow-up phone cal…

This study looks at whether eating 4-5 servings of dairy foods daily (like milk, cheese, and yogurt) can improve brain function and thinking skills in overweight adults aged 40-75. Participants will be randomly assigned to a high-dairy or low-dairy diet for several weeks. Researc…

This study looks at how healthy young adults digest and absorb protein from beef. Ten participants will eat minced beef alone or as part of a mixed meal on two separate days. Researchers will track amino acids in the blood to see how the body processes the protein. This is an obs…

This study looks at whether the way you spread out your daily protein intake affects how much muscle protein your body builds, both at rest and after resistance exercise. Thirty-six healthy adults aged 18-40 will be assigned to one of three protein distribution patterns (one larg…

This study tests a non-invasive imaging technique called LC-OCT for diagnosing basal cell carcinoma, the most common skin cancer. Researchers will review medical records of about 300 patients to see if LC-OCT can accurately detect cancer and guide treatment without needing a biop…

This study looks at how different protein sources (plant-based vs. dairy) and mild electrical muscle stimulation affect muscle building during 4 days of bed rest in 20 healthy young adults. The goal is to find better ways to prevent muscle loss in hospitalized patients. Participa…

This study follows 750 adults with liver cirrhosis to see how the disease progresses when doctors use remote monitoring as part of standard care. Participants share their medical and monitoring data, but no new treatment or device is tested. The goal is to track complications lik…

This study looks for the ideal amount of protein healthy young adults need to maximize muscle building. Twelve people aged 18-35 will try different protein drinks in a random order. The goal is to find the smallest protein amount that still gives the best muscle-building effect.