Fred Hutchinson Cancer Center

This study tests whether the drug ustekinumab can prevent acute graft-versus-host disease (GVHD) in adults with blood cancers who receive a stem cell transplant from an unrelated donor. GVHD occurs when donor cells attack the patient's body. The trial involves 116 participants an…

This early-phase study tests a new targeted drug (PVEK) combined with standard chemotherapy for adults with aggressive, hard-to-treat blood cancers like acute myeloid leukemia (AML). The drug homes in on a marker found on cancer cells to deliver chemotherapy directly. The goal is…

This study tests a strong chemotherapy combination followed by a stem cell transplant to treat autoimmune neurologic diseases like multiple sclerosis and stiff person syndrome. The goal is to weaken the immune system so it stops attacking the nervous system. About 53 adults whose…

This early-stage trial tests a drug called DR-18 in 20 adults whose acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) has come back or persists after a stem cell transplant. DR-18 is designed to boost the body's immune system to fight cancer cells. The main goals are…

This study looks at different screening methods to find early signs of cervical cancer in women living with HIV in the Dominican Republic. The goal is to see which approach—like testing for HPV—works best to catch precancerous changes early. About 619 women aged 25 to 49 will tak…

This study tests a program designed to help men who have sex with men in Lima, Peru get tested for HIV and connect to treatment or prevention services. The program offers HIV testing at popular social venues and provides a text-messaging app with health information and support fr…

This study tests whether giving patients processed fecal material (fecal microbiota transplantation) after a stem cell transplant can prevent severe graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial involves 138 adults…

This study tests a program called HOPE that helps women with recurrent ovarian cancer cope with feelings of hopelessness and helplessness. About 60 participants will either take part in the HOPE workshops or receive usual care. The goal is to see if the program improves mental he…

This study tests whether a personalized program can help cancer survivors become more physically active and improve their diet. It involves 374 adult survivors of childhood or young adult cancers who are not very active. The program uses coaching, mobile apps, and goal-setting to…

This study tests a program called MIND that delivers nutrition and cooking lessons online to breast cancer survivors. The goal is to see if it helps improve diet quality and increase fruit and vegetable intake. About 49 people with stage I-III breast cancer will participate, and …

This study aimed to test a smartphone app called EQQUAL-NM, designed to help LGBTQ+ young adults (ages 18-30) in New Mexico quit smoking. The app used a culturally-tailored avatar to guide users. However, the study was withdrawn before enrolling any participants, so no results ar…

This study looks at whether new guidelines from the National Institutes of Health can help doctors better diagnose and track chronic graft-versus-host disease (GVHD), a common complication after stem cell transplants. Researchers are following 601 patients over several years, col…

This study involves 383 people with chronic Graft-versus-Host Disease (GVHD), a complication after stem cell transplant. Researchers are developing and testing new measurement tools to better determine if treatments are working. The goal is to create more accurate ways to assess …