New combo therapy aims to boost immune attack on Hard-to-Treat lymphoma
NCT ID NCT05359211
First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times
Summary
This early-stage trial tests whether adding an experimental drug called NKTR-255 to standard CAR-T cell therapy can safely improve outcomes for adults with large B-cell lymphoma that has returned or stopped responding to treatment. The drug is designed to strengthen the immune system's cancer-fighting cells. About 27 participants will receive the combination and be monitored for side effects and tumor response.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.