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New tools could help doctors predict who will respond to chronic GVHD therapies

NCT ID NCT01902576

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This study involves 383 people who have chronic graft-versus-host disease (GVHD) after a stem cell transplant. Researchers are developing and testing new ways to measure whether a treatment is working, including a symptom-based activity index and a score that predicts long-term success without treatment failure. The goal is to create better tools for future clinical trials and patient care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, 98109, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could provide doctors with better ways to measure if a chronic GVHD treatment is working, and help predict which patients will respond to which therapies.

What could go wrong

This is an observational study focused on developing measurement tools, not testing a new treatment. The tools may not prove accurate enough for widespread use, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

chronic graft versus host disease graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.