Erasmus Medical Center

This study tests a new way to deliver radiotherapy for kidney cancer that uses advanced imaging to target the tumor more precisely. The goal is to reduce radiation damage to healthy kidney tissue. About 40 adults with non-spreading kidney cancer will receive this treatment. Resea…

This study tests a new way to treat atrial fibrillation (AFib), a common heart rhythm problem. Doctors will use a special catheter that delivers short electrical pulses to isolate the veins causing the issue. After 2-3 months, participants will have a second procedure to see if t…

This study tests whether adding an intra-aortic balloon pump (IABP) to standard VA-ECMO support helps more patients with cardiogenic shock successfully wean off ECMO within 30 days. About 430 adults will be randomly assigned to receive either ECMO alone or ECMO plus IABP. The goa…

This study compares two common drugs, cyclosporine and methotrexate, to treat moderate-to-severe alopecia areata in children aged 2-17. The goal is to see which medicine helps regrow hair better over 9 months. Participants and their parents choose which treatment to try, and doct…

This study tests a new treatment for stomach cancer that has spread to the lining of the belly (peritoneal metastases). About 55 patients will receive chemotherapy directly into the abdomen along with standard intravenous chemotherapy, and possibly immunotherapy or targeted thera…

This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people who have a positive ctDNA blood test (a sign of leftover cancer cells). About 103 adults with high-risk rectal cancer will either receive chemo or be observed. The goal i…

This study tests a tool called SCALE-EYE that helps doctors measure the size of polyps during a colonoscopy. The goal is to see if it works better than current methods and can reduce the number of follow-up colonoscopies, waste, and carbon footprint. About 241 people aged 55-80 h…

This study tests a program called HoorToren, which includes seven classroom lessons and four home assignments, to see if it can help children aged 10-11 use headphones more safely. Researchers will compare 600 kids who get the program with those who don't, using questionnaires an…

This study tests whether listening to music before and after electroconvulsive therapy (ECT) can reduce postictal agitation—a common side effect where patients become restless or confused after treatment. Researchers will enroll 92 adults with severe depression undergoing ECT. Ha…

This study tests whether a 12-week home-based high intensity interval training program can improve exercise capacity in people aged 12 to 45 who have a congenital heart defect requiring a right ventricle to pulmonary artery conduit. Participants will be assigned to either an imme…

This study looks at whether a home-based computer cognitive training program can help adults with acquired brain injury (like from a stroke) improve their thinking skills, such as memory and attention. About 30 people receiving outpatient rehab will be randomly assigned to either…

This study tests whether adding a program that targets sleep and stress (called RESST) to standard cardiac rehabilitation helps heart patients recover better. About 200 adults with heart conditions who also have poor sleep or high stress will take part. Researchers will measure s…

This study follows 150 children and adults worldwide who have ultra-rare mutations in CAMK2 genes, which cause developmental delays, seizures, and autism-like traits. Researchers will collect data on milestones, behavior, and seizures to create detailed disease maps. The goal is …

This study aims to create a standard set of questions that combines dentist-reported outcomes and patient-reported outcomes to better evaluate dental implant success. Researchers will enroll 1,000 patients aged 18-70 across 30 dental practices in the Netherlands and Spain. Partic…

This study checks if it's possible to send some hospital patients home early and monitor them remotely using a smartphone app and vital sign tracking. Researchers want to see if at least 30% of eligible patients can safely use this virtual ward. The goal is to reduce hospital sta…

This study investigates the 'measles paradox'—how measles can temporarily weaken the immune system while also providing lifelong protection. Researchers will track immune memory cells in 300 adults before and after measles infection. The goal is to understand how measles causes i…

This study is testing whether people with pulmonary fibrosis can safely replace half of their regular clinic visits with home monitoring. Participants will use a home spirometer, pulse oximeter, and a smartphone app to track their health and communicate with their care team. The …

This study looks at whether a quick bedside test can measure fibrinogen levels in trauma patients with severe bleeding within minutes, instead of the usual 30-45 minutes. Fibrinogen helps blood clot, and low levels can worsen bleeding. The test is being checked for feasibility an…

This study looks at whether a small drop of blood from a finger-prick device can reliably detect tumor DNA in 35 adults with colorectal cancer that has spread to the liver. Researchers will compare results from the finger-prick sample to a standard arm-vein blood draw to see if t…