Erasmus Medical Center

This early-stage trial tests a therapeutic vaccine called ISA104 in 24 people with chronic hepatitis B who are already on antiviral drugs. The goal is to see if the vaccine is safe and can boost the immune system to better fight the virus. Participants will receive either ISA104 …

This study tests whether taking potassium supplements can slow down kidney function loss in people with moderate-to-severe chronic kidney disease (CKD) and high blood pressure. About 532 adults with CKD stage 3b or 4 will receive potassium or a placebo. The goal is to see if pota…

This study looks at a new method of clamping the umbilical cord for babies born with a congenital diaphragmatic hernia (a hole in the diaphragm). The standard approach is to clamp the cord right away, but this may worsen lung blood pressure. The new method waits until the baby's …

This study looks at whether taking a daily multivitamin can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like tirzepatide) for weight loss. About 246 adults with obesity who have been on a stable GLP-1 dose for at least 3 months will be randomly assigned …

This study tests whether giving chemotherapy both before and after surgery helps people with pancreatic cancer live longer compared to chemotherapy only after surgery. About 378 patients with resectable pancreatic cancer will be randomly assigned to one of two treatment schedules…

This study looks at whether an MRCP scan can accurately measure liver fat instead of a biopsy in people who want to donate part of their liver. A biopsy is invasive and carries risks, while an MRCP is safer and faster. Researchers will compare results from both methods in 90 dono…

This study tests a computer dashboard that helps doctors and nurses manage pain in newborns in the intensive care unit (NICU). The dashboard shows when a baby might be in pain so the care team can act quickly. Researchers will check if the dashboard reduces the time babies spend …