Erasmus Medical Center

This study tests a new way to give chemotherapy for stomach cancer that has spread to the lining of the abdomen. The drug irinotecan is given directly into the belly along with standard chemo drugs. The goal is to see if this combination is safe and doable for patients. About 55 …

This study tests a new treatment for atrial fibrillation (AF), a common heart rhythm problem. Twenty adults with AF will receive a procedure using the VARIPULSE system, which uses short electrical pulses to isolate the veins causing the issue. After 2-3 months, participants will …

This study tests whether giving chemotherapy after surgery can prevent rectal cancer from returning in people who have a positive ctDNA blood test (a sign of leftover cancer cells). About 103 adults with high-risk rectal cancer will either receive chemo or be observed. The goal i…

This study compares two drugs, cyclosporine and methotrexate, to see which works better for children aged 2-17 with moderate-to-severe alopecia areata, a condition causing patchy hair loss. About 50 children will choose their preferred treatment and be followed for 9 months. The …

This study tests whether adding a balloon pump (IABP) to standard ECMO support helps people with severe cardiogenic shock recover their heart function. About 430 adults will be randomly assigned to receive ECMO alone or ECMO plus the balloon pump. The main goal is to see if more …

This study is testing a new way to give radiation to kidney tumors. The goal is to use advanced imaging to target the tumor more precisely, reducing radiation to the healthy part of the kidney. About 40 adults with kidney cancer that has not spread will take part. The main focus …

This study tests a program called HoorToren that teaches 10-11 year old children how to listen to music safely through headphones or earbuds. About 600 Dutch primary school children will take part, with half receiving the lessons and the other half not. Researchers will measure i…

This study looks at whether a home-based computer cognitive training program can help adults with acquired brain injury (like from a stroke) improve their thinking skills, such as memory and attention. About 30 people receiving outpatient rehab will be randomly assigned to either…

This study tests whether a 12-week home-based high intensity interval training program can improve exercise capacity in people aged 12 to 45 with a congenital heart defect that required a surgical connection between the right ventricle and pulmonary artery. Participants will be a…

This study tests whether adding a program that targets sleep and stress (called RESST) to standard cardiac rehabilitation helps heart patients recover better. About 200 adults with heart conditions who also have poor sleep or high stress will take part. Researchers will measure s…

This study collects health information from 150 children and adults worldwide who have an ultra-rare genetic condition affecting the CAMK2 genes. Researchers will track developmental milestones, seizures, and behaviors to create detailed maps of how the disease progresses. The go…

This study looks at whether a quick bedside test can measure fibrinogen levels in trauma patients with severe bleeding within minutes, instead of the usual 30-45 minutes. Fibrinogen helps blood clot, and low levels can worsen bleeding. The test is being checked for feasibility an…

This study looks at whether a small drop of blood from a finger-prick device can reliably detect tumor DNA in 35 adults with colorectal cancer that has spread to the liver. Researchers will compare results from the finger-prick sample to a standard arm-vein blood draw to see if t…

This study checks if it's possible to send some hospital patients home early and monitor them remotely using a smartphone app and vital sign tracking. The goal is to see if at least 30% of eligible patients can safely be cared for at home instead of staying in the hospital. Aroun…