Erasmus Medical Center

This study tests whether adding a special heart pump (IABP) helps people on ECMO recover from severe cardiogenic shock. About 430 adults will be randomly assigned to get ECMO alone or ECMO plus the pump. The main goal is to see if more patients can successfully come off ECMO with…

This study compares two medicines, cyclosporine and methotrexate, for treating moderate-to-severe alopecia areata in children aged 2 to 17. The goal is to see which one works better for regrowing hair and improving quality of life. Participants and their families choose which tre…

This study is testing a new way to deliver radiation to kidney tumors that uses advanced imaging to target the cancer more precisely. The goal is to reduce radiation damage to the healthy part of the kidney, helping to preserve kidney function. The study will enroll 40 adults wit…

This study tests a new way to treat atrial fibrillation (AF), a common heart rhythm problem. The procedure uses short electrical pulses to isolate the veins that cause the irregular heartbeat. Twenty adults with AF will receive this treatment, and after 2-3 months, doctors will c…

This study tests a tool called SCALE-EYE that helps doctors measure the size of polyps during a colonoscopy. It compares SCALE-EYE to the standard method using biopsy forceps. The goal is to see if SCALE-EYE is more accurate and can reduce the number of colonoscopies needed, as w…

This study tests a program called HoorToren that teaches 10-11 year old children how to listen to music safely through headphones. About 600 Dutch primary school children will take part, with half receiving the lessons and half not. Researchers will check if the program changes k…

This study tests whether playing music during recovery from electroconvulsive therapy (ECT) can reduce postictal agitation—a common side effect where patients become restless or confused. About 92 adults with severe depression will be monitored for agitation after their ECT sessi…

This study tests whether a 12-week home-based high intensity interval training program can improve exercise capacity in people aged 12 to 45 who have a congenital heart defect requiring a special connection between the right heart chamber and lung artery. Participants will be ass…

This study tests whether adding a special program for sleep and stress (called RESST) to standard cardiac rehabilitation helps heart patients recover better. About 200 adults with heart conditions who have trouble sleeping or feel stressed will take part. Researchers will track s…

This study tests whether giving iron through a vein after a heart valve procedure (TAVI) can improve quality of life and walking ability in older adults with low iron. About 402 people aged 65 and older will be randomly assigned to receive iron infusions or standard care. The goa…

This study checks if it's possible to send some hospital patients home early and monitor them remotely using a smartphone app and vital sign checks. About 306 adults who are stable enough will be offered this virtual ward. The goal is to see if at least 30% of eligible patients c…

This study looks at whether a small drop of blood from a finger-prick device can reliably detect tumor DNA in 35 adults with colorectal cancer that has spread to the liver. Researchers will compare these results with standard blood draws from a vein to see if the simpler method w…

This study aims to solve the measles paradox: how the virus can temporarily weaken the immune system, increasing risk of other infections, while also providing lifelong protection against measles itself. Researchers will follow 300 adults, including those who get measles or the M…

This study collects health information from 150 children and adults worldwide who have a rare genetic condition caused by changes in CAMK2 genes. Researchers will track developmental milestones, seizures, and behaviors to create detailed maps of how the disease progresses. The go…

This study aims to create a Dental Implant Standard Set that combines patient-reported outcomes with clinical measures to better evaluate dental implant success. Researchers will enroll 1,000 patients aged 18-70 across 30 dental practices in the Netherlands and Spain. Participant…