New Cord-Clamping method may ease lung pressure in rare birth defect
NCT ID NCT04373902
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times
Summary
This study looks at a different way of clamping the umbilical cord after birth for babies born with a hole in their diaphragm (congenital diaphragmatic hernia). The new method, called physiological-based cord clamping, waits until the baby's lungs have filled with air before clamping. The goal is to see if this reduces dangerous high blood pressure in the lungs during the first day of life. About 140 babies with left-sided defects will take part across multiple hospitals.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Erasmus MC University Medical Center - Sophia Children's Hospital
Rotterdam, Netherlands
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Karolinska University Hospital
Stockholm, Sweden
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Medical University Graz
Graz, Austria
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Monash University
Melbourne, Australia
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Ospedale Pediatrico Bambino Gesu
Rome, Italy
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Radboudumc University Medical Center
Nijmegen, Netherlands
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University Hospitals leuven
Leuven, Belgium
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Universitätsklinik Mannheim
Mannheim, Germany
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Universitätskrankenhaus Bonn
Bonn, Germany
Conditions
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