Changhai Hospital

This early-stage study is testing a new treatment called anti-CD19/BCMA universal CAR T cells for people with relapsed or refractory immune-mediated kidney disease. The therapy uses specially engineered immune cells to target and attack faulty B cells that drive the disease. The …

This study tests whether combining an immunotherapy drug (toripalimab) with standard BCG therapy can stop high-risk bladder cancer from coming back after tumor removal surgery. About 31 adults with aggressive non-muscle-invasive bladder cancer will receive the combo treatment for…

This study tests a new treatment called anti-CD19/BCMA universal CAR-T cells for people with severe autoimmune diseases like lupus, scleroderma, and rheumatoid arthritis that haven't responded to standard therapies. The treatment uses specially engineered immune cells to target a…

This study tests a drug called hetrombopag to prevent low platelet counts caused by chemotherapy in people with gastrointestinal tumors (like stomach or colon cancer). About 40 participants will take the pill daily for 14 days after chemo. The goal is to see if it keeps platelet …

This study tests a new approach to treat high-risk bladder cancer without removing the bladder. It combines a special freezing technique (cryoablation) with standard tumor removal, immunotherapy, and low-dose chemotherapy. The goal is to see if this combination can improve surviv…

This study tests whether transplanting healthy gut bacteria (FMT) can prevent serious infections in people with moderate to severe acute pancreatitis. About 80 adults will receive either FMT or a placebo. The goal is to see if FMT lowers the risk of infected pancreatic tissue, se…

This study tests a new treatment for people with advanced pancreatic cancer whose tumors have a specific genetic change (KRAS G12V) and a certain immune type (HLA-A*11:01). The treatment uses the patient's own immune cells, modified in a lab to recognize and attack cancer cells. …

This early-phase study tests a new treatment called CAR-NK cells (CL-NK-003) in 9 people with advanced pancreatic cancer that has not responded to standard therapies. The goal is to check safety and see if the cells can shrink tumors or slow the disease. Participants receive a si…

This study tests an artificial intelligence system that analyzes contrast-enhanced CT scans to help doctors decide the best course of action for people with suspected pancreatic diseases. The AI will classify patients into three groups: needing immediate treatment, close monitori…

This study tests whether giving extra fluids through a vein along with a standard anti-inflammatory medicine (indometacin) can better prevent pancreatitis after a procedure that uses shock waves to break up painful stones in the pancreas. About 1,250 adults with chronic pancreati…

This study tests if transplanting healthy gut bacteria (fecal microbiota transplantation) can prevent infections like pneumonia and infected pancreatic tissue in people with severe acute pancreatitis. About 150 adults aged 18-75 with moderate to severe disease will receive the tr…

This study tests whether a pre-packaged low-residue diet helps people with inflammatory bowel disease (IBD) prepare for a colonoscopy more comfortably and effectively. About 500 adults with IBD will either follow this special diet or standard prep. The goal is to see if the diet …

This study tests whether a pre-packaged low-residue diet (Maifu Changqing® Complete Nutrition Formula Powder) helps people with inflammatory bowel disease (IBD) prepare for a colonoscopy more comfortably while still cleaning the bowel effectively. About 1,000 adults with IBD will…

This study looks at how well people with inflammatory bowel disease (IBD) prepare their bowels before a colonoscopy. Researchers want to find out what factors lead to poor preparation and create a tool to predict who might have trouble. The goal is to make bowel prep more persona…

This study is creating a large collection of medical images and lab results to help doctors better detect early upper gastrointestinal cancers and precancerous changes. Researchers will gather images from capsule endoscopy, standard endoscopy, and CT scans, along with tissue samp…