Changhai Hospital

This early-phase study tests a new treatment called anti-CD19/BCMA universal CAR T cells (KN3601) for people with relapsed or refractory immune-mediated kidney disease. The therapy involves collecting a patient's immune cells, engineering them to target and destroy harmful B cell…

This study tests whether the drug hetrombopag can prevent low platelet counts caused by chemotherapy in people with gastrointestinal cancers like stomach or colon cancer. About 40 participants will take the drug daily for 14 days after each chemo cycle. The goal is to keep platel…

This study tests whether transplanting healthy gut bacteria (FMT) can reduce serious infections in people with moderate to severe acute pancreatitis. About 80 adults will receive either FMT or a placebo. The goal is to see if FMT lowers the risk of infected pancreatic tissue, sep…

This study tests a new approach to treat high-risk bladder cancer without removing the bladder. It combines freezing the tumor during surgery with immunotherapy and low-dose chemotherapy. The goal is to see if this combination can help patients live longer and keep their bladder,…

This early-stage study tests a new treatment called CAR-NK cells (CL-NK-003) in 9 people with advanced pancreatic cancer that has not responded to standard therapies. The main goal is to check safety and find the right dose. Researchers will also watch for signs that the treatmen…

This early-phase study tests a new type of CAR-T cell therapy (called KN3601) for people with severe autoimmune diseases like lupus, scleroderma, Sjögren's syndrome, rheumatoid arthritis, and vasculitis that haven't responded to standard treatments. The therapy uses specially eng…

This study tests a new treatment for people with advanced pancreatic cancer that has a specific genetic change (KRAS G12V). The treatment uses the patient's own immune cells, modified in a lab to better recognize and attack cancer cells. The goal is to see if this therapy is safe…

This study tests whether adding the immunotherapy drug toripalimab to standard BCG treatment can stop high-risk bladder cancer from returning after surgery. About 31 adults with aggressive non-muscle-invasive bladder cancer will receive the combination for 6 months. The goal is t…

This study tests an artificial intelligence system that reads contrast-enhanced CT scans to help doctors decide the best course of action for pancreatic diseases. The AI sorts patients into three groups: need treatment, need close monitoring, or routine follow-up. Researchers aim…

This study tests whether fecal microbiota transplantation (FMT) can prevent serious infections in people with moderately severe or severe acute pancreatitis. About 150 adults will receive either FMT or a placebo through a feeding tube. The goal is to see if FMT lowers the chance …

This study tests whether giving extra IV fluids along with a standard anti-inflammatory suppository can better prevent pancreatitis after a procedure to break up pancreatic stones. About 1250 adults with chronic pancreatitis will be randomly assigned to receive either the combina…

This study tests whether a lower dose (50mg) of rectal indomethacin works as well as the standard dose (100mg) to prevent pancreatitis after an ERCP procedure. About 1,366 adults scheduled for ERCP will be randomly assigned to receive either dose 30 minutes before the procedure. …

This study tests whether a pre-packaged low-residue nutrition formula (Maifu Changqing®) can improve bowel cleanliness and comfort during colonoscopy preparation for 1,000 adults with inflammatory bowel disease (IBD). Participants will be randomly assigned to receive either the s…

This study tests whether a pre-packaged low-residue diet (Maifu Changqing®) helps people with inflammatory bowel disease (IBD) prepare for colonoscopy more comfortably and effectively. About 500 adults with IBD will be enrolled across multiple hospitals in China. The goal is to s…

This study involves 1,000 adults with inflammatory bowel disease (IBD) who need a colonoscopy. Researchers want to see how well current bowel preparation methods work and what factors lead to poor preparation. The goal is to create a tool that predicts which patients might have t…

This study is gathering images from special cameras and CT scans, along with lab results, to create a database for early upper gastrointestinal cancers and precancerous conditions. About 500 adults who need certain procedures will take part. The goal is to help doctors better rec…