Centre Oscar Lambret

This study looked at whether adding a specific chemotherapy combination (carboplatin and paclitaxel) after standard chemoradiation could help people with advanced cervical cancer that has spread to lymph nodes in the abdomen. The trial planned to enroll 21 participants but was st…

This study tested the drug imatinib in adults with ocular (eye) melanoma that had spread to other parts of the body. The goal was to see if the drug could stop or shrink tumors. Only 13 people took part before the study was stopped early.

This study tested a new treatment plan for people with stage IB2 to IVA cervical cancer. It combined radiation and two chemotherapy drugs (gemcitabine and cisplatin), followed by more chemo with gemcitabine alone. The goal was to see if this sequence could improve how long patien…

This study tested whether a special light technique called Narrow Band Imaging (NBI) can help surgeons find early cancer spots in the mouth that are hard to see with the naked eye. The trial included 23 adults with untreated oral cancer who were scheduled for surgery. The goal wa…

This study looked at whether giving radiation to the brain early could prevent cancer from spreading there in people with HER2-positive breast cancer that had already spread to other organs. All participants were receiving trastuzumab (Herceptin) plus chemotherapy. The study was …

This study tested a technique that helps people with advanced cancer and their partners organize traumatic memories and practice slow breathing to reduce PTSD symptoms. The approach aimed to shift how the brain processes trauma, moving from emotional reactions to more controlled …

This study looked at whether a mechanical stimulation technique could reduce pain and improve shoulder function better than standard massages in women who had a total mastectomy and lymph node removal for breast cancer. About 80 participants were planned, but the study was stoppe…

This study aimed to see how radiosurgery (a precise type of radiation) impacts the quality of life of people with brain metastases that have spread from other cancers. Researchers planned to follow 52 adults with up to 5 brain tumors for one year, tracking their physical and ment…

This study looked at the best way to monitor the lungs of people who had surgery for a high-grade soft tissue sarcoma. The goal was to see if a simple chest X-ray or a more detailed CT scan was better at finding lung cancer spread early. Only 11 people took part before the study …

This study looked at 21 people with advanced lung cancer to see if a blood test (liquid biopsy) could find EGFR gene mutations as accurately as a standard tumor biopsy. Researchers compared results from three different lab methods. The goal was to improve how doctors detect these…

This study tested whether MRI and PET scans could predict if cervical cancer would be controlled by radiation therapy. It included 9 people with stage I to IIIB cervical cancer. The study was stopped early, so results are limited.

This study aimed to find the best cell source for creating a non-stick patch to prevent adhesions in cancer patients. Researchers compared cells from the peritoneum and from fat tissue to see which could form a protective mesothelial layer. Only 6 adults participated before the s…

This study looked at why people with mouth or throat cancer delay their first doctor visit. Researchers interviewed 90 adults with untreated cancer to understand how feelings, beliefs, and social factors affect the time between noticing symptoms and getting help. The goal was to …

This study tested a biodegradable balloon placed between the prostate and rectum to see if it could reduce radiation damage to the rectum during prostate cancer treatment. The study enrolled 24 men with intermediate-risk prostate cancer. The main goal was to measure how much the …

This study looked at how high-dose radiation therapy affects the immune system in people with liver, colorectal, melanoma, or kidney cancers. Researchers took blood samples before, during, and after treatment to track immune cells and other markers. The goal was to learn more abo…

This study looked at whether giving women with breast cancer extra emotional and practical help early on could improve their chances of returning to work. It included 128 women who had surgery and chemotherapy. The study was stopped early, so results are limited.

This study looked at breast cancer stem cells, which are thought to be the root of tumor growth and resistance to standard treatments like chemotherapy. Researchers collected tumor samples and blood from 56 women before, during, and after chemotherapy to track how these stem cell…

This study aimed to understand how chemotherapy impacts the ability to have children in young women (ages 18-37) with breast cancer. Researchers measured ovarian reserve using hormone levels and follicle counts before, during, and up to 24 months after treatment. The goal was to …

This study collected blood, fluid, and tissue samples from 36 women with advanced ovarian or fallopian tube cancer to analyze immune cells before and after chemotherapy. The goal was to understand how the immune system responds to the cancer and treatment. The study was terminate…

This study looked at whether the types of bacteria in a person's gut before treatment could predict how well their rectal cancer responds to chemotherapy and radiation. Researchers planned to collect stool samples from patients with stage II or III rectal cancer and compare their…

This study aimed to find out if patients with metastatic esophageal cancer who were not getting worse after 6 weeks of chemotherapy should continue treatment or stop. Only 15 people took part before the study was ended early. The goal was to see if continuing chemo helped patient…