Centre Oscar Lambret

This study looks at whether giving the HPV vaccine to women over 45 who still have the virus after treatment for high-grade cervical lesions can help clear the infection. About 85 women will take part, with some receiving the vaccine and others not. The main goal is to see if the…

This study tests a special low-dose chemotherapy schedule (metronomic chemo) in children aged 1.5 to 17 years whose Wilms tumor has come back or not responded to standard treatments. The goal is to see if this approach can stop the tumor from growing after two treatment cycles. A…

This study tests three treatments for long-term nerve pain after mastectomy: a nerve block (SPB), Botox, or capsaicin. 123 women whose pain is not controlled by standard medication will be randomly assigned to one of the three groups. The main goal is to see which treatment reduc…

This study tests whether a Snoezelen multisensory relaxation room can reduce anxiety in children aged 8 to 17 who are hospitalized for chemotherapy. Participants will compare their feelings during a chemo cycle without Snoezelen to a later cycle with 45-minute Snoezelen sessions …

This study tests whether a gentle radiofrequency treatment inside the vagina can reduce dryness and pain in breast cancer patients taking hormone therapy. About 75 women will either receive standard moisturizers alone or moisturizers plus three radiofrequency sessions. The goal i…

This study looks at 371 people with advanced ovarian, peritoneal, or fallopian tube cancer to find out which patient and tumor traits affect how long they live. Researchers will collect medical data and blood samples over 2 years. The goal is to build a database that helps doctor…

This study is creating a detailed database of 651 adults with solid tumors who are starting immunotherapy. Researchers will track their health over 5 years to see how well these treatments work in everyday medical practice. The goal is to learn more about outcomes like survival a…

This study collects tumor and blood samples from 100 breast cancer patients to grow mini-tumors (organoids) in the lab. Researchers will then test whether specially engineered immune cells called CAR-macrophages can kill these organoids. The goal is to learn which types of breast…

This study looks at whether a digital, personalized care plan can help people with advanced sarcoma who are on chemotherapy. About 377 participants will either get the digital plan plus standard care, or standard care alone. The main goal is to see if the digital plan reduces sev…

This study looks at whether follow-up care for people with rare tumors can be done just as well by a nurse remotely as by a doctor in person. About 88 adults recently diagnosed with a rare tumor will be randomly assigned to either in-person doctor visits or remote nurse check-ins…