Sarcoma lung surveillance study halted early: x-ray vs CT debate unresolved
NCT ID NCT01612481
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to compare chest X-ray and CT scans for detecting lung metastases in people who had surgery for high-grade soft tissue sarcoma. Only 11 patients were enrolled before the study was terminated early. The goal was to see which method better finds isolated, operable lung spread, but the small size limits what can be learned.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help determine the best way to monitor for lung cancer spread after sarcoma surgery, potentially reducing unnecessary scans and anxiety.
- What could go wrong
- The study was terminated early with only 11 participants, so results are very limited and may not provide clear answers. It is a small, early-phase trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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11 people
The number who actually took part.
- Started
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Apr 2012
- Finished
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May 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * soft tissue sarcoma, histologically proven * tumor size \> 5 cm (SBR grade 2) or whatever size (SBR grade 3) * complete excision (R0 or R1) * no metastasis (checked by spiral chest CT) * social security covered * informed signed consent Exclusion Criteria: * bone, visceral, uterine, retroperitoneal sarcoma * GIST * other malignant tumor * patients over 70, or for whom thoracic surgery is excluded * pneumoconiosis or known system disease * breast feeding or pregnant woman * patient unable to undergo trail medical follow up for geographic, social or psychological reasons
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Georges François Leclerc
Dijon, 21079, France
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Léon BERARD Center
Lyon, 69008, France
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Oscar Lambret Center
Lille, 59020, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Marine-Derived drug slow advanced soft tissue sarcoma?
- Can a One-Two punch of immunotherapy and radiation tame sarcoma before surgery?
- Can a radioactive antibody light up hidden tumors?
- A simple blood test may reveal hidden infertility risk in young cancer survivors
- Could a massive tissue bank unlock sarcoma's secrets?