Baylor Research Institute
Clinical trials sponsored by Baylor Research Institute, explained in plain language.
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Womb transplants offer hope for women born without a uterus to have a baby
⭐️ CURE ⭐️ OngoingThis study is testing whether transplanting a uterus from a living or deceased donor can allow women who cannot get pregnant due to not having a working uterus to have a baby. The trial involves 20 women who have healthy ovaries. After the transplant, doctors will help them try t…
Phase: NA • Sponsor: Baylor Research Institute • Aim: ⭐️ CURE ⭐️
Last updated Mar 31, 2026 12:12 UTC
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Study tests easier eye treatment after cataract surgery
Disease control TerminatedThis study aimed to compare two treatments for controlling inflammation after cataract surgery in patients with diabetes. It would have tested a single-insert treatment (Dextenza) against the standard multi-week eye drop regimen (prednisolone). The goal was to see if the simpler …
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 04, 2026 03:36 UTC
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New lifestyle program aims to tackle weight gain after brain injury
Disease control OngoingThis study is testing a 12-month group lifestyle program adapted for people who have had a moderate to severe traumatic brain injury (TBI). The goal is to see if the program helps participants lose weight and improve their overall health by promoting healthy eating and physical a…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 04, 2026 03:35 UTC
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Spice extract tested as potential alternative to cervical surgery
Disease control TerminatedThis early-stage study aimed to see if taking curcumin, the active compound in turmeric, could help treat a precancerous condition of the cervix called CIN3. The plan was for participants to take curcumin pills twice daily for 12 weeks to see if the abnormal cells would shrink or…
Phase: EARLY_PHASE1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Recovered Patients' blood tested as potential COVID-19 treatment
Disease control TerminatedThis early study aimed to test whether plasma (the liquid part of blood) from people who recovered from COVID-19 could help hospitalized patients with COVID-19 pneumonia. The idea was that antibodies in the recovered patients' plasma might help fight the virus in sick patients. T…
Phase: PHASE1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug duo tested for Tough-to-Treat esophageal cancer
Disease control OngoingThis early-stage study is testing the safety and effectiveness of combining two drugs, abemaciclib and ramucirumab, for people with advanced esophageal or gastroesophageal junction cancer that has spread. The trial is for patients whose cancer has continued to grow despite receiv…
Phase: PHASE1, PHASE2 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New program aims to help stroke survivors shed pounds and boost health
Disease control OngoingThis study is testing a year-long healthy lifestyle program specifically designed for people who have had a stroke. The program focuses on better eating and increased physical activity to help participants lose weight. Researchers want to see if this approach improves weight, fit…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Could a simple pill fix a painful swallowing problem?
Disease control OngoingThis small, early-stage study is testing whether a two-week course of steroid pills can improve muscle function in adults with a swallowing disorder called EGJOO. Researchers suspect the condition might be linked to an allergic reaction in the esophagus. The goal is to see if thi…
Phase: EARLY_PHASE1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Virtual program aims to help brain injury survivors shed pounds and boost health
Disease control OngoingThis study is testing whether a proven weight loss program can work just as well when delivered by video call to people who have had a moderate to severe traumatic brain injury (TBI). The goal is to make the program more accessible, especially for underserved groups. Researchers …
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New drug combo aims to stop liver Cancer's return after transplant
Disease control ENROLLING_BY_INVITATIONThis study is testing if adding a drug called everolimus to standard anti-rejection medications after a liver transplant can better prevent liver cancer from coming back. It will involve about 336 adults with advanced liver cancer who receive a transplant. Researchers will compar…
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Chilling idea to stop dangerous Post-Birth bleeding
Disease control TerminatedThis study aimed to see if using cold saline to inflate a special balloon placed in the uterus could better control severe bleeding after childbirth compared to using room-temperature saline. It was designed for women aged 18-45 who had just delivered vaginally and were experienc…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Safer blood thinners for life support? new study aims to reduce deadly bleeding and clots
Disease control OngoingThis study is testing if giving a common blood thinner (heparin) as a shot under the skin is as safe and effective as the standard method of giving it directly into a vein for patients on a lung life support machine called ECMO. The goal is to find the best way to prevent dangero…
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New test aims to clear athletes for play after head injury
Diagnosis ENROLLING_BY_INVITATIONThis study is testing a new exercise assessment called CASE to help doctors decide when young athletes can safely return to sports after a concussion. Researchers will measure heart rate, blood pressure, and symptoms during sport-like exercises in 125 athletes aged 10-22 who have…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Diagnosis
Last updated Mar 25, 2026 14:09 UTC
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Firefighters train peers to build mental resilience before crisis hits
Prevention ENROLLING_BY_INVITATIONThis study is testing a special workshop, led by fellow firefighters, that teaches emotion regulation skills. It aims to prevent PTSD, depression, anxiety, and alcohol use problems in new firefighter recruits. Researchers will compare this workshop to standard mental health educa…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Doctors question routine antibiotics after common prostate procedure
Prevention TerminatedThis study aimed to find out if taking antibiotics for three days after a common laser surgery for an enlarged prostate (HoLEP) actually prevents urinary tract infections. It planned to compare men who received the antibiotics to those who did not. The goal was to help doctors av…
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Three-Session therapy aims to stop PTSD before it starts in spinal injury patients
Prevention ENROLLING_BY_INVITATIONThis study is testing whether a brief, three-session therapy can prevent post-traumatic stress disorder (PTSD) in people recovering from spinal cord injuries. Researchers are comparing this special therapy to standard rehabilitation care in 200 patients during their hospital reco…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Prevention
Last updated Mar 02, 2026 15:27 UTC
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New recovery plan aims to cut opioid use after kidney transplants
Symptom relief ENROLLING_BY_INVITATIONThis study is testing a special recovery program designed to help people feel less pain after kidney transplant surgery. The program includes steps like drinking a special pre-surgery drink, taking specific pain medications before surgery, getting numbing medicine at the surgical…
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Apr 02, 2026 15:00 UTC
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Could a beam of light slow dementia?
Symptom relief OngoingThis study is testing whether shining a special near-infrared light on the head can help improve memory, attention, and thinking in people with early to mid-stage dementia. Researchers want to see if this light can boost brain cell activity and support the brain's own repair proc…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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New injection aims to cut opioid use after surgery
Symptom relief TerminatedThis study aimed to test if a special pain-blocking injection given during surgery could help patients use fewer opioid painkillers afterward. It focused on people having weight loss surgery or other minimally invasive stomach procedures. The trial planned to compare two differen…
Phase: PHASE2, PHASE3 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Mar 25, 2026 14:07 UTC
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Zapping a nerve to rewire the brain? new hope for spinal injury patients
Symptom relief OngoingThis study is testing whether a small implanted device that gently stimulates a neck nerve (the vagus nerve) can help the brain and spinal cord rewire themselves during physical therapy. The goal is to improve arm and hand strength and function for people living with chronic spin…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Researchers ask: what stops people from joining cancer studies?
Knowledge-focused OngoingThis study aims to understand why people might not sign up for cancer prevention research. Researchers are interviewing patients to identify common barriers to enrollment. The goal is to use this feedback to make future studies more accessible and trustworthy for everyone in the …
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Anesthesia's hidden impact on swallowing disorder diagnosis revealed
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how different anesthesia drugs affect measurements of esophageal muscle function during a diagnostic test called FLIP topography. Researchers will enroll 30 adults with swallowing disorders like achalasia who are undergoing a specific endoscopic proc…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC