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Robotic exoskeleton training may help restore walking after spinal injury

NCT ID NCT05218447

Disease control Sponsor: Baylor Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial investigates how different amounts of robotic gait training using an exoskeleton, combined with brain stimulation, affect walking ability in people with spinal cord injury. Participants with motor incomplete injuries will train during inpatient and outpatient rehab. The study measures changes in walking speed, independence, and brain plasticity to find the best training dose.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Robotic exoskeleton (Ekso GT™) and transcranial magnetic stimulation
What this could lead to
If successful, this could establish effective dosing for robotic gait training to improve walking and independence after spinal cord injury.
What could go wrong
This is an early-stage dosing study, not a large confirmatory trial. Results may not lead to a standard therapy, and individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

98 people

The number who actually took part.

Started

May 2022

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All types of motor incomplete SCI (traumatic and non-traumatic) * Acute/Subacute phase of recovery * Medically stable as deemed by physician * Undergoing medical care and rehabilitation at Baylor Scott \& White Institute for Rehabilitation * Both genders and all races and ethnicities * Meet the Ekso robotic exoskeleton frame limitations * Continence of or a program for bladder and bowel management Exclusion Criteria: * Concurrent moderate to severe traumatic brain injury (TBI) * Degenerative diagnoses * Pre-morbid developmental disability, significant psychological diagnosis, or other cognitive impairment * Pregnancy

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injuries

Contacts and locations

Locations

  • Baylor Scott & White Institute for Rehabilitation

    Dallas, Texas, 75246, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.