Baylor College Of Medicine

This early-phase trial tests whether adding vitamin C to standard steroid treatment helps people with gastrointestinal graft-versus-host disease (GVHD), a serious complication after a donor stem cell transplant. About 35 participants aged 5 and older will receive vitamin C plus s…

This study compares two approved cyclosporine eye drops—Vevye (0.1%) and a generic (0.05%)—in 60 adults with dry eye disease. Over 8 weeks, researchers will measure changes in goblet cells, which produce mucus to keep eyes moist. Participants use drops daily and visit the clinic …

This early-stage trial tests a new treatment for children with a rare, aggressive brain tumor called ATRT that has come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified in a lab to better recognize and attack the tumor, plus a…

This pilot trial will test a disposable endoscope in 40 adults undergoing POEM procedures for achalasia or gastroparesis. The goal is to see if the single-use scope works as well as standard reusable scopes, potentially reducing infection risk. All participants receive standard c…

This early-phase trial tests a new type of cell therapy for people with metastatic HER2-positive breast cancer that has worsened after standard treatment. Researchers take a patient's own immune cells (T cells), add new genes to help them recognize and attack cancer cells, and re…

This study tests whether platelet-rich plasma (PRP) injections can help treat central centrifugal cicatricial alopecia (CCCA), a scarring hair loss that mostly affects women of African descent. PRP is made from a patient's own blood and is thought to reduce inflammation and promo…

This study looks for brain-based markers (biomarkers) of obsessive-compulsive disorder (OCD) in people with severe, hard-to-treat symptoms. Participants complete decision-making tasks and are exposed to personal OCD triggers while their brain activity is recorded with EEG and the…

This study will test whether a simple skin scan can accurately measure how many fruits and vegetables toddlers eat. Researchers will give 150 healthy 2-year-olds either applesauce or a fruit-vegetable puree for 4 weeks, then compare skin carotenoid levels with blood tests and foo…

This study will follow 12 people with severe OCD or bipolar disorder who are already scheduled to receive deep brain stimulation (DBS). Researchers will use the DBS device to record brain activity while participants wear smart rings, watches, and phones to track sleep, activity, …