Baylor College Of Medicine

This early-phase study is testing a new treatment for cancers linked to the human papillomavirus (HPV) that have come back or not responded to standard care. Researchers take a patient's own immune cells, grow and modify them in a lab to better recognize and attack HPV-infected c…

This study is comparing two different types of surgical knives used during a minimally invasive procedure to remove precancerous growths (polyps) in the colon. Researchers want to see if a newer 'bipolar' knife is faster and causes fewer side effects like abdominal pain than the …

This early-phase study is testing the safety of a new cell therapy for patients with Hodgkin's or Non-Hodgkin's lymphoma that has come back after standard treatment. Doctors collect a patient's own immune cells, genetically modify them in a lab to better recognize and attack lymp…

This early-phase study is testing the safety of a new treatment for people with recurrent or treatment-resistant brain tumors that have a specific marker called HER2. Doctors take a patient's own immune cells (T cells), modify them in a lab to better recognize and attack the canc…

This early-phase study is testing a new type of cell therapy called AGAR T cells in children and young adults with solid tumors that have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and…

This early study tested whether adding a drug called AZA to standard steroid treatment could better control a serious complication called graft-versus-host disease (GVHD) that affects the gut after a transplant. The goal was to see if this combination was safe and could protect t…

This study is testing whether a protein supplement called carnitine can reduce artery stiffness in teenagers who are at risk for future heart problems. Researchers will give carnitine or a placebo to 90 teens with high triglycerides for six months to see if it improves artery hea…

This study is comparing two ways to perform a delicate surgery on unborn babies with spina bifida, a serious spinal cord defect. Doctors are testing if using a collagen patch during a minimally invasive 'fetoscopic' repair leads to a stronger, thicker closure of the defect compar…

This early-stage study is testing a new combination treatment for children and young adults with advanced osteosarcoma or neuroblastoma that has come back or hasn't responded to standard therapies. Doctors take a patient's own immune cells, genetically modify them to better recog…

This study is testing whether Invisalign clear aligners are a safe and effective way to straighten teeth for people with Osteogenesis Imperfecta (OI), also known as brittle bone disease. Traditional braces are often too risky for people with OI because their tooth enamel is fragi…

This is an early-stage safety study testing a new type of cell therapy for adults with certain recurring B-cell blood cancers (like lymphoma, myeloma, or CLL) that have not responded to standard treatments. Doctors take a patient's own immune cells (T cells), genetically modify t…

This early-stage study is testing a new type of cell therapy for acute myeloid leukemia (AML) that has returned or not responded to standard treatments. Doctors take a patient's own immune cells (T cells), modify them in a lab to better recognize and attack the leukemia cells, an…

This is an early-stage safety study testing a new type of treatment for patients whose B-cell lymphoma or leukemia has returned or not responded to standard therapies. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to better recognize and at…

This study is testing a modified bone marrow transplant procedure for adults and children with serious blood cancers and disorders. The goal is to treat the underlying disease while reducing the risk of a dangerous complication called graft-versus-host disease. Researchers use a …

This study tests a new treatment for cancers linked to the Epstein-Barr virus (EBV) that have come back or haven't responded to standard care. Doctors are using a bank of pre-made immune cells from healthy donors, which are specially trained to attack EBV-infected cancer cells, a…

This study is testing a new cell therapy for lymphoma that has come back after treatment and is linked to Epstein-Barr virus (EBV). Researchers are giving patients special immune cells (T cells) that have been genetically modified to resist a substance released by the tumor and t…

This early-stage study is testing a new therapy for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has returned or persists after standard treatment, including a stem cell transplant. Researchers take immune cells (T cells) from the patient's orig…

This early-stage study is testing a new type of treatment called CATCH T cells in adults with advanced solid tumors that have a specific marker (GPC3). Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer, and then infu…

This early-stage study is testing a new treatment called GAP T cells in children and young adults with liver cancer that has come back or hasn't responded to standard treatments. Doctors take a patient's own immune cells, genetically modify them in a lab to recognize and attack c…

This study is testing a new treatment for advanced sarcoma, a type of cancer. Doctors take a patient's own immune cells (T-cells), genetically modify them in a lab to recognize and attack cancer cells, and then infuse them back into the patient. The main goals are to find the saf…

This early-phase study is testing the safety of a new cell therapy for patients whose blood cancer (like leukemia or lymphoma) has come back after a stem cell transplant from a donor. Doctors take immune cells (T cells) from the donor, genetically modify them in a lab to better r…

This early-stage study is testing a new type of cell therapy for patients with EBV-positive nasopharyngeal cancer that has returned or not responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cancer cells…

This study is testing if a non-invasive headband device, already approved for migraines, can help reduce seizures in veterans with epilepsy that doesn't respond well to medication. 24 veterans will try using the device along with their usual care to see if it lowers how often the…

This study aims to find better ways to screen men for early signs of cancers caused by HPV, particularly in the throat and genital areas. Researchers are testing whether specific markers in blood and oral samples can identify men at higher risk before cancer develops. About 1,500…

This study is testing a new, advanced ultrasound otoscope device to see if it can accurately diagnose middle ear infections in children. Researchers are collecting images and data from 300 children who are already scheduled for ear tube surgery. They will compare the device's rea…

This study is testing if mailing a simple, at-home HPV test kit can help more Asian and Asian American women get screened for cervical cancer. It focuses on women in a safety-net healthcare system who are overdue for their regular screening. The goal is to see if this convenient,…

This study is testing whether chewing xylitol gum during pregnancy can improve oral and vaginal bacteria, reduce gum inflammation, and potentially benefit infant development. Researchers in Malawi are enrolling 80 pregnant women who will chew either xylitol or placebo gum daily f…

This study is testing whether a brief home visitation program can help pregnant women and new mothers. It aims to help them connect to community resources, feel more confident about their health, and reduce stress. The program is delivered by trained non-nurse visitors and is bei…

This study aimed to see if adding ear acupuncture during surgery could help patients use fewer opioid painkillers after having a broken ankle repaired. It planned to compare patients who received the acupuncture along with standard pain control to those who received standard care…

This study is testing if a simple oral care treatment helps babies born with gastroschisis, an abdominal wall defect, recover better. Researchers are applying small amounts of the mother's breast milk (or sterile water if milk isn't available) to the baby's cheek to see if it imp…

This study is testing two different online therapy programs designed to help parents support their children with anxiety or obsessive-compulsive disorder (OCD). It involves 100 children aged 7-13 in Texas and compares these parent-led, therapist-supported online programs to a sim…

This study aimed to see if adding ear acupuncture during wrist fracture surgery could help patients use fewer opioid painkillers afterward. It planned to compare two groups of adults getting the same surgery and standard pain plan, with only one group receiving the acupuncture. T…

This study aimed to see if a pill containing synthetic THC, the main active part of cannabis, could safely help reduce chronic pelvic pain in women with endometriosis. It was a small, early-stage trial where some participants would have received the THC pill and others a placebo …

This study aims to understand how donor human milk affects the long-term growth and brain development of very small premature infants after they leave the hospital. Researchers will follow 51 infants, born weighing 1250 grams or less, who received donor milk. They will track the …

This study aims to better understand dental and jaw problems in people with Osteogenesis Imperfecta (OI), also known as brittle bone disease. Researchers will use 3D scans and X-rays to measure teeth misalignment and neck defects in 75 participants aged 10 and older who have mode…

This study aims to understand how osteogenesis imperfecta (brittle bone disease) affects lung and heart function. Researchers will examine 18 adults with the condition through questionnaires, physical exams, and imaging tests during a single visit. The goal is to learn why breath…

This study aims to see if a new urine test can help doctors better understand and classify different types of Osteogenesis Imperfecta (OI), a rare condition that makes bones break easily. Researchers will collect urine samples from 25 people with OI who have specific genetic muta…

This study is checking on children who were very premature babies to see if the amount of protein they received in their hospital milk diet affects their growth, body composition, and brain development by age 2. It follows up on 120 infants who were part of an earlier hospital st…