Baylor College Of Medicine

This study tested different versions of an experimental hookworm vaccine in healthy adults who had never had hookworm. Participants received three vaccine shots or a placebo, and were later exposed to a small, controlled dose of hookworm larvae to see if the vaccine prevented inf…

This study tested a new vaccine designed to prevent schistosomiasis, a serious disease caused by parasitic worms. Researchers gave the vaccine to 290 healthy adults in Uganda to check if it was safe and if it could protect them from getting infected. They tested different doses a…

This early study tested adding a daily oral drug called atovaquone to the standard, strong chemotherapy used for children and young adults newly diagnosed with acute myeloid leukemia (AML). The main goal was to see if patients could tolerate taking atovaquone alongside chemo with…

This study tested a new counseling program called THRIVE for hospitalized people with HIV who had fallen out of regular care. The program used Acceptance and Commitment Therapy to help patients overcome avoidance, stigma, and mental health barriers that keep them from attending a…

This study tested whether adding extra vitamin D to special formula helps preterm babies maintain healthy vitamin D levels and supports their bone development. Researchers compared two different vitamin D amounts in 39 preterm infants born between 28 and 34 weeks. They measured v…

This study tested a new treatment for children with high-risk neuroblastoma, a type of cancer. Researchers took a patient's own immune cells, modified them in a lab to better recognize and attack cancer cells, and then gave them back to the patient. The main goals were to check i…

This study tested whether adding a prescription sleep medication (lemborexant) to a standard alcohol treatment drug (naltrexone) could help people with alcohol use disorder. The goal was to see if the combination reduced alcohol cravings and improved sleep quality better than the…

This study tested whether giving very small premature babies (under 1000g) a high-protein human milk diet would help them grow better and develop healthier body composition compared to a standard protein diet. Researchers randomly assigned 118 infants to receive either the high-p…

This early-phase study tested the safety of a modified chemotherapy regimen, called dose-adjusted EPOCH-R, in children with aggressive B-cell cancers like diffuse large B-cell lymphoma. The treatment involved giving some drugs as a continuous infusion over four days and adjusting…

This early-phase study tested a new gene therapy approach for patients whose non-Hodgkin lymphoma or chronic lymphocytic leukemia had returned or didn't respond to standard treatments. Researchers modified patients' own immune T-cells in the lab to better recognize and attack the…

This study tested an experimental therapy using a patient's own immune cells, specially grown in a lab to recognize and attack pancreatic cancer. It involved 37 adults whose cancer had returned, was not responding to standard treatments, or who were scheduled for surgery. The mai…

This study tested a peer support program for young adults (ages 17-25) with type 1 diabetes as they move from pediatric to adult healthcare. Trained mentors, who also have type 1 diabetes, provided guidance and shared their own experiences over 12 months. The main goal was to see…

This study tested if adding a concentrated cream made from human milk to regular breast milk helps very small premature babies gain weight better. It involved 78 infants born weighing between 1.6 and 2.8 pounds. Babies were randomly assigned to receive either milk with the extra …

This study tested whether adding a calorie-boosting cream made from human milk to the diet of very premature babies could help them leave the hospital earlier. Researchers compared 210 tiny babies who received the cream supplement to those who did not. They also checked if the cr…

This study compared two types of biopsy needles used during endoscopic ultrasound procedures to diagnose pancreatic masses. Researchers collected tissue samples from 52 adult patients with pancreatic lesions to see which needle type provided better quality samples for lab testing…

This study tested if a simple program using a Fitbit activity tracker and encouraging text messages could help Hispanic teenagers with obesity become more active and sleep longer. The goal was to see if these healthy habit changes could lower their risk of developing type 2 diabe…

This study tested if mailing HPV self-test kits to women's homes could help more underserved women get screened for cervical cancer. Researchers compared three different outreach methods, including phone calls and mailed kits, to see which worked best. The goal was to find a prac…

This small, completed pilot study tested whether a smartphone app delivering guided imagery therapy could help children with chronic functional abdominal pain. Kids aged 7-12 were randomly assigned to either use the app immediately or after an 8-week wait. The main goal was to se…

This study tested whether adding acupuncture during gallbladder removal surgery helps prevent nausea and vomiting afterward. Researchers compared patients who received standard anti-nausea medications plus acupuncture to those who received only the medications. The goal was to se…

This study tested whether a special therapy program for anxiety could work well in local community centers for autistic children and teens. Researchers adapted a proven talk therapy to be more accessible and studied if families and clinics could use it. The goal was to see if thi…

This study observed the standard care given to very small premature babies who were fed donor human milk in the hospital. Researchers tracked 150 infants to see if their electrolyte levels (like sodium and phosphorus) stayed normal and if doctors followed monitoring guidelines. N…

This study aimed to find out if simple body measurements could predict which of two common treatments would work better for children with chronic stomach pain. Researchers tested 163 children aged 7-12 to see if their heart rate, gut bacteria, or other body signals could show whe…

This study observed children who stayed overnight in the hospital after having surgery to treat sleep apnea. Researchers monitored their oxygen levels to better understand which patients actually need this overnight monitoring and which could safely go home sooner. The goal is to…