Aarhus University Hospital

This study looks at whether a surgery called subtotal parathyroidectomy can improve bone density, physical function, and quality of life in people who still have high calcium or low phosphate levels after a kidney transplant. About 85 adults who had a kidney transplant at least 6…

This study looks at whether people with an ACL tear can get better with rehabilitation alone, without surgery. Researchers will track 400 participants' knee function, symptoms, and how many end up needing surgery anyway. The goal is to see if non-surgical treatment is a good opti…

This early-phase trial tests two existing drugs—senicapoc and perampanel—alone and together for newly diagnosed glioblastoma, the most common and aggressive adult brain cancer. The goal is to find safe doses and see if the drugs reach the tumor. About 36 adults will receive the d…

This study is testing whether denosumab, a drug used for osteoporosis, can also improve muscle strength and insulin sensitivity in postmenopausal women with type 2 diabetes. About 40 women will receive either denosumab or a placebo for 12 months. The goal is to see if the drug of…

This study tests whether using a special camera that makes parathyroid glands glow (autofluorescence) during thyroid cancer surgery can reduce the risk of hypoparathyroidism, a condition where calcium levels drop. About 160 adults having their thyroid removed for cancer will be r…

This study looks at people whose MRI scans show small areas of brain damage called covert brain infarcts (CBIs), which are linked to a higher risk of future stroke and dementia. Researchers want to see if giving stroke-preventing medications (antiplatelets or statins) can reduce …

This study tests a treatment called remote ischemic conditioning (RIC) for people who have had a brain aneurysm bleed. RIC involves briefly inflating a blood pressure cuff on the arm to restrict blood flow, which may protect the brain. The study will compare recovery and brain da…

This study is testing whether using a special blanket for 4 weeks can improve sleep in 672 young people aged 16-24 who have trouble sleeping. Participants will be randomly assigned to use one of two special blankets or no blanket at all. The goal is to find a safe, non-drug way t…

This study looks at whether a comprehensive geriatric assessment (CGA) before and after bladder cancer surgery can help older, frail patients recover faster. About 140 patients aged 65 and older who are scheduled for cystectomy will receive either standard care or a CGA with a pe…

This study tests whether a weekly dose of cabergoline can reduce the number of migraine days in adults who have 4 to 14 migraines per month. About 150 participants will receive either a low dose, a higher dose, or a placebo for 12 weeks, followed by 12 weeks where everyone gets t…

This study aims to find more tuberculosis (TB) cases by improving diagnostic tools already available in low-resource clinics. About 1,584 adults with TB symptoms in Guinea-Bissau and Ethiopia will be tested using enhanced methods like instructed sputum collection, chest X-rays wi…

This study looks at how radiotherapy for anal cancer affects women's vaginal and sexual health. Researchers will examine 80 women who completed treatment 6 to 36 months ago, using gynecological exams and questionnaires. The goal is to link radiation dose to vaginal problems and i…

This study follows 20 people with Parkinson's disease who have a brain procedure called focused ultrasound to stop tremors. Researchers want to find out why some people's tremors return within two years. Participants will have brain scans and tests before and after treatment to h…

This study looks at a treatment called SIRT (selective internal radiation therapy) for people with colorectal cancer that has spread to the liver and hasn't responded to other treatments. The main goal is to learn more about the biology of the cancer and find markers that might p…

This study uses data from about 475 people with acute lymphoblastic leukemia (ALL) who have received the drug Erwinase. The goal is to create a computer model that helps doctors give the right dose to balance effectiveness and reduce side effects like high ammonia levels. The res…