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Beyond survival: new study examines hidden side effects of anal cancer treatment

NCT ID NCT07296237

Knowledge-focused Sponsor: Aarhus University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This observational study follows 80 women treated with chemoradiotherapy for anal cancer to understand how radiation affects their vaginal and sexual health. Participants will have a gynecological exam, complete questionnaires about quality of life and sexual health, and allow researchers to analyze their radiation scans. The goal is to link radiation dose to vaginal problems and improve future support for patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better prevent, detect, and treat vaginal and sexual problems after radiotherapy, improving quality of life for future patients.
What could go wrong
This is an observational study with only 80 participants, so results may not apply to all women. It does not test a new treatment, so it won't directly change care yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population includes adult women who have been treated with chemoradiotherapy for anal cancer in Denmark. Participants are recruited during routine follow-up visits at three oncology departments. All participants are between 6 and 36 months after treatment and are in cancer follow-up care

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18 years or older * Diagnosed with anal cancer * Treated with chemoradiotherapy with curative intent * Between 6 and 36 months since completion of radiotherapy * Able and willing to give written informed consent Exclusion Criteria: * Previous pelvic radiotherapy for another disease * Treated with electron beam radiotherapy * Unable to speak or understand Danish

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Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

anal carcinoma anus neoplasm physiological sexual disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anal cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Oncology Aarhus University Hospital (AUH)

    RECRUITING

    Aarhus, 8200, Denmark

  • Department of Oncology Vejle Hospital, University Hospital of Southern Denmark

    RECRUITING

    Vejle, 7100, Denmark

  • Department of Oncology, Herlev and Gentofte Hospital

    RECRUITING

    Herlev, 2730, Denmark

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