Skip the knife? new study tests rehab-only for ACL tears
NCT ID NCT04408885
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether people with an ACL knee injury can get better with rehabilitation alone, without surgery. Researchers will track 400 participants to see how their knee functions and how many end up needing surgery. The goal is to find out if non-surgical treatment is a good option for some patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2020
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
We will include 400 patients with Anterior cruciate ligament injury. Patients will be included at different orthopaedic Clinics at 5 hospitals in Region Midtjylland.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Anterior cruciate ligament injury where rehabilitation regime is selected as treatment. Exclusion Criteria: * Other knee ligament instability * Rheumatoid arthritis * Morbus Bechterews Disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Division of Sports Trauma, Palle Juul-Jensens Boulevard 99
RECRUITINGAarhus N, 8200, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Light against pain: laser and infrared go head to head in ACL rehab
- 24 sensors map muscle oxygen after ACL surgery
- Which workout rebuilds a repaired knee best? a head-to-head trial of movement vs stability training
- Stem cell byproduct may boost ACL graft healing — trial puts it to the test
- Bone scaffold may help ACL grafts heal stronger
- Wearable shirt tracks surgeon fatigue during knee surgery