THYROID CANCER

This study is testing whether the immunotherapy drug pembrolizumab (Keytruda) can help control advanced anaplastic thyroid cancer, a rare and aggressive form of the disease. The trial includes 12 adults with cancer that cannot be surgically removed or has spread, and who have no …

This study is testing whether using a laser to heat and destroy very small thyroid cancers is a safe and effective alternative to surgery. It will involve 10 patients who have a tiny papillary thyroid cancer but do not want to just watch and wait. Doctors will use a needle to gui…

This study is testing whether combining an immunotherapy drug (pembrolizumab) with a chemotherapy drug (docetaxel) can help control advanced thyroid and salivary gland cancers that have stopped responding to standard treatments. It will involve about 46 adults with these specific…

This study tested pembrolizumab, an immunotherapy drug, in people with advanced solid tumors who had already tried standard treatments that stopped working. Researchers enrolled 1,609 participants with various cancers including anal, cervical, lung, and thyroid cancers to see how…

This study is testing if a drug called vemurafenib can shrink thyroid tumors before surgery in patients with advanced cancer. The drug targets a specific genetic mutation found in the cancer cells. Researchers will measure changes in tumor size and certain biomarkers after 56 day…

This study is testing whether combining an immunotherapy drug called PDR001 with other targeted cancer drugs is safe and effective for treating advanced thyroid cancer that no longer responds to standard radioactive iodine treatment. The trial includes 19 adults with specific typ…

This study compares two surgical approaches for low-risk thyroid cancer to determine which leads to better long-term outcomes. Patients with early-stage thyroid cancer were randomly assigned to receive either standard thyroid removal alone or thyroid removal plus additional lymph…

This study is testing whether the drug regorafenib can help control metastatic medullary thyroid cancer that has continued to grow despite prior treatments. It is for adults whose cancer has worsened within the last 6 months and who have already tried at least one other targeted …

This study aims to validate a new molecular test to better determine if thyroid nodules are cancerous. It involves 71 patients with inconclusive biopsy results. The goal is to improve diagnosis so fewer people undergo surgery for benign nodules.

This study is testing whether a new artificial intelligence (AI) tool can help doctors more accurately and quickly diagnose thyroid diseases from ultrasound images. It involves 2,000 adults across 16 hospitals in China who are already getting thyroid ultrasounds for suspected pro…

This study is testing a new way to take pictures of cancer tumors using a special light called Cerenkov luminescence. The goal is to see if this method can clearly show tumors in areas like the neck, armpit, or groin. The study involves 102 adults with thyroid cancer or other can…

This study aims to understand why breast tissue sometimes shows up on radioactive iodine scans in women treated for thyroid cancer. Researchers are comparing two different preparation methods for the scan to see if one affects a specific hormone (prolactin) more, and if that horm…

This study is testing whether an artificial intelligence (AI) assistant can help medical students and doctors more accurately determine the stage and risk level of thyroid cancer from patient notes. 70 participants will review cases, with half using the AI tool and half not, to s…

This study looks at whether patients who have a small thyroid lump found by chance during a PET scan need a follow-up ultrasound. Researchers are comparing the long-term survival rates of 5,000 people who got an ultrasound within 3 months to those who did not. The goal is to see …

This study aimed to understand if thyroid surgery changes the thickness of neck arteries, which is linked to future heart disease and stroke risk. Researchers planned to measure artery thickness before and after surgery in adults with various thyroid conditions. The goal was to g…